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Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria

IMBB researchers uncover a novel molecular mechanism for Nucleotide Excision Repair during mammalian development. Kamileri et al reveal that key proteins in this pathway activate the transcription of genes involved in mammalian growth.