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Small heat-shock proteins protect from heat-stroke-associated neurodegeneration

Small heat-shock proteins protect from heat-stroke-associated neurodegeneration

Research at IMBB, published today in the premier international scientific journal Nature, uncovers a universal and potent protective mechanism against neuronal necrosis. By developing and characterizing models of heat stroke, Kourtis and Nikoletopoulou in theTavernarakis lab reveal a novel molecular mechanism that defends against neurodegeneration triggered by extreme temperature and multiple, diverse insults.