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The role of VEGF Signaling and UPR in Angiogenesis

The role of VEGF Signaling and UPR in Angiogenesis

The team of Prof. Theo Fotsis reveals that VEGF integrates components of the UPR machninery to generate angiogenesis. In this repsect, Karali et al. show that the ER plays an important role in normal cellular functions, such as signaling by growth factors, and is not limited to the adaptation of the cell to stress.

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