Publications


•  Chatzidakis I, Mamalaki C. T cells as sources and targets of TNF: implications for immunity and autoimmunity. Curr Dir Autoimmun 2010;11:105-118.

•  Sarasa-Renedo A, Favicchio R, Birk U, Zacharakis G, Mamalaki C, Ripoll J. Source intensity profile in noncontact optical tomography. Opt Lett 2010;35:34-36.

•  Klaus M, Stavroulaki E, Kastrinaki MC, Fragioudaki P, Giannikou K, Psyllaki M, Pontikoglou C, Tsoukatou D, Mamalaki C, Papadaki HA. Reserves, functional, immunoregulatory, and cytogenetic properties of bone marrow mesenchymal stem cells in patients with myelodysplastic syndromes. Stem Cells Dev 2010;19:1043-1054.

•  Bertsias GK, Nakou M, Choulaki C, Raptopoulou A, Papadimitraki E, Goulielmos G, Kritikos H, Sidiropoulos P, Tzardi M, Kardassis D, Mamalaki C, Boumpas DT. Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus. Arthritis Rheum 2009;60:207-218.

•  Martin A, Aguirre J, Sarasa-Renedo A, Tsoukatou D, Garofalakis A, Meyer H, Mamalaki C, Ripoll J, Planas AM. Imaging changes in lymphoid organs in vivo after brain ischemia with three-dimensional fluorescence molecular tomography in transgenic mice expressing green fluorescent protein in T lymphocytes. Mol Imaging 2008;7:157-167.

•  Meyer H, Garofalakis A, Zacharakis G, Psycharakis S, Mamalaki C, Kioussis D, Economou EN, Ntziachristos V, Ripoll J. Noncontact optical imaging in mice with full angular coverage and automatic surface extraction. Appl Opt 2007;46:3617-3627.

•  Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J. Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact Chatzidakis I, Fousteri G, Tsoukatou D, Kollias G, Mamalaki C. An essential role for TNF in modulating thresholds for survival, activation, and tolerance of CD8+ T cells. J Immunol 2007;178:6735-6745.

•  Papadimitraki ED, Choulaki C, Koutala E, Bertsias G, Tsatsanis C, Gergianaki I, Raptopoulou A, Kritikos HD, Mamalaki C, Sidiropoulos P, Boumpas DT. Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum 2006;54:3601-3611.

•  Stamou P, de Jersey J, Carmignac D, Mamalaki C, Kioussis D, Stockinger B. Chronic exposure to low levels of antigen in the periphery causes reversible functional impairment correlating with changes in CD5 levels in monoclonal CD8 T cells. J Immunol 2003;171:1278-1284.

•  Drabek D, Zagoraiou L, deWit T, Langeveld A, Roumpaki C, Mamalaki C, Savakis C, Grosveld F. Transposition of the Drosophila hydei Minos transposon in the mouse germ line. Genomics 2003;81:108-111.

•  Zagoraiou L, Drabek D, Alexaki S, Guy JA, Klinakis AG, Langeveld A, Skavdis G, Mamalaki C, Grosveld F, Savakis C. In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissues. Proc Natl Acad Sci U S A 2001;98:11474-11478.

•  Pascolo S, Tsoukatou D, Mamalaki C. Identification of thymus specific and developmentally regulated genes by an improved version of the mRNA differential display technique. Dev Immunol 1999;7:1-7.

•  Wen L, Wong FS, Burkly L, Altieri M, Mamalaki C, Kioussis D, Flavell RA, Sherwin RS. Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice. J Clin Invest 1998;102:947-957.

•  Tarazona R, Williams O, Moskophidis D, Smyth LA, Tanaka Y, Murdjeva M, Wack A, Mamalaki C, Kioussis D. Susceptibility and resistance to antigen-induced apoptosis in the thymus of transgenic mice. J Immunol 1998;160:5397-5403.

•  Melton E, Sarner N, Torkar M, van der Merwe PA, Russell JQ, Budd RC, Mamalaki C, Tolaini M, Kioussis D, Zamoyska R. Transgene-encoded human CD2 acts in a dominant negative fashion to modify thymocyte selection signals in mice. Eur J Immunol 1996;26:2952-2963.

•  Mamalaki C, Murdjeva M, Tolaini M, Norton T, Chandler P, Townsend A, Simpson E, Kioussis D. Tolerance in TCR/cognate antigen double-transgenic mice mediated by incomplete thymic deletion and peripheral receptor downregulation. Dev Immunol 1996;4:299-315.

•  Festenstein R, Tolaini M, Corbella P, Mamalaki C, Parrington J, Fox M, Miliou A, Jones M, Kioussis D. Locus control region function and heterochromatin-induced position effect variegation. Science 1996;271:1123-1125.

•  Pihlgren M, Lightstone L, Mamalaki C, Rimon G, Kioussis D, Marvel J. Expression in vivo of CD45RA, CD45RB and CD44 on T cell receptor-transgenic CD8+ T cells following immunization. Eur J Immunol 1995;25:1755-1759.

•  Murdjeva M, Mamalaki C, Kioussis D. Identification of the thymic stromal populations which participate in the negative selection of double positive thymocytes. Folia Med (Plovdiv) 1995;37:26.

•  Law YM, Yeung RS, Mamalaki C, Kioussis D, Mak TW, Flavell RA. Human CD4 restores normal T cell development and function in mice deficient in murine CD4. J Exp Med 1994;179:1233-1242.

•  Kramer S, Mamalaki C, Horak I, Schimpl A, Kioussis D, Hung T. Thymic selection and peptide-induced activation of T cell receptor-transgenic CD8 T cells in interleukin-2-deficient mice. Eur J Immunol 1994;24:2317-2322.

•  Corbella P, Moskophidis D, Spanopoulou E, Mamalaki C, Tolaini M, Itano A, Lans D, Baltimore D, Robey E, Kioussis D. Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity. Immunity 1994;1:269-276.

•  Casabo LG, Mamalaki C, Kioussis D, Zamoyska R. T cell activation results in physical modification of the mouse CD8 beta chain. J Immunol 1994;152:397-404.

•  Tanaka Y, Mamalaki C, Stockinger B, Kioussis D. In vitro negative selection of alpha beta T cell receptor transgenic thymocytes by conditionally immortalized thymic cortical epithelial cell lines and dendritic cells. Eur J Immunol 1993;23:2614-2621.

•  Mamalaki C, Tanaka Y, Corbella P, Chandler P, Simpson E, Kioussis D. T cell deletion follows chronic antigen specific T cell activation in vivo. Int Immunol 1993;5:1285-1292.

•  Mamalaki C, Elliott J, Norton T, Yannoutsos N, Townsend AR, Chandler P, Simpson E, Kioussis D. Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen. Dev Immunol 1993;3:159-174.

•  Homer RJ, Mamalaki C, Kioussis D, Flavell RA. T cell unresponsiveness correlates with quantitative TCR levels in a transgenic model. Int Immunol 1993;5:1495-1500.

•  Robey EA, Ramsdell F, Gordon JW, Mamalaki C, Kioussis D, Youn HJ, Gottlieb PD, Axel R, Fowlkes BJ. A self-reactive T cell population that is not subject to negative selection. Int Immunol 1992;4:969-974.

•  Mamalaki C, Norton T, Tanaka Y, Townsend AR, Chandler P, Simpson E, Kioussis D. Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice. Proc Natl Acad Sci U S A 1992;89:11342-11346.

•  Lang G, Mamalaki C, Greenberg D, Yannoutsos N, Kioussis D. Deletion analysis of the human CD2 gene locus control region in transgenic mice. Nucleic Acids Res 1991;19:5851-5856.

•  Mamalaki C, Barnard EA, Stephenson FA. Molecular size of the gamma-aminobutyric acidA receptor purified from mammalian cerebral cortex. J Neurochem 1989;52:124-134.

•  Lo MM, Conrad MK, Mamalaki C, Kadan MJ. Retroviral-mediated gene transfer. Applications in neurobiology. Mol Neurobiol 1988;2:155-182.

•  Mamalaki C, Stephenson FA, Barnard EA. The GABAA/benzodiazepine receptor is a heterotetramer of homologous alpha and beta subunits. Embo J 1987;6:561-565.

•  Stephenson FA, Mamalaki C, Casalotti SO, Barnard EA. The GABAA receptor and its antibodies. Biochem Soc Symp 1986;52:33-40.

•  Stephenson FA, Casalotti SO, Mamalaki C, Barnard EA. Antibodies recognising the GABAA/benzodiazepine receptor including its regulatory sites. J Neurochem 1986;46:854-861.

•  Sigel E, Mamalaki C, Barnard EA. Reconstitution of the purified gamma-aminobutyric acid-benzodiazepine receptor complex from bovine cerebral cortex into phospholipid vesicles. Neurosci Lett 1985;61:165-170.

•  Sigel E, Stephenson FA, Mamalaki C, Barnard EA. The purified GABA/benzodiazepine/barbiturate receptor complex: four types of ligand-binding sites, and the interactions between them, are preserved in a single isolated protein complex. J Recept Res 1984;4:175-188.

•  Barnard EA, Stephenson FA, Sigel E, Mamalaki C, Bilbe G, Constanti A, Smart TG, Brown DA. Structure and properties of the brain GABA/benzodiazepine receptor complex. Adv Exp Med Biol 1984;175:235-254.

•  Sigel E, Stephenson FA, Mamalaki C, Barnard EA. A gamma-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex. J Biol Chem 1983;258:6965-6971.

•  Sigel E, Mamalaki C, Barnard EA. Isolation of a GABA receptor from bovine brain using a benzodiazepine affinity column. FEBS Lett 1982;147:45-48.