Poirazi P, Papoutsi A. (2020) Illuminating dendritic function with computational models. Nat Rev Neurosci. 21:303-321.

Gidon A, Zolnik TA, Fidzinski P, Bolduan F, Papoutsi A, Poirazi P, Holtkamp M, Vida I, Larkum ME. (2020) Dendritic action potentials and computation in human layer 2/3 cortical neurons. Science. 367:83-87.

Park J, Papoutsi A, Ash RT, Marin MA, Poirazi P, Smirnakis SM. (2019) Contribution of apical and basal dendrites to orientation encoding in mouse V1 L2/3 pyramidal neurons. Nat Commun. 10:5372.

Tzilivaki A, Kastellakis G, Poirazi P. (2019) Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators. Nat Commun. 10:3664.

Turi GF, Li WK, Chavlis S, Pandi I, O'Hare J, Priestley JB, Grosmark AD, Liao Z, Ladow M, Zhang JF, Zemelman BV, Poirazi P, Losonczy A. (2019) Vasoactive Intestinal Polypeptide-Expressing Interneurons in the Hippocampus Support Goal-Oriented Spatial Learning. Neuron. 101:1150-1165.

Pubmed: https://pubmed.ncbi.nlm.nih.gov/?term=poirazi
Google Scholar: https://scholar.google.com/citations?hl=el&user=7IidNJMAAAAJ&view_op=list_works&sortby=pubdate

Journal Publications

2021

Sehgal M, Filho D A, Martin S, Mejia D I, Kastellakis G, Kim S, Lee J, Pekcan A, Huang S, Lavi A, Heo W D, Poirazi P, Trachtenberg J, Silva A. "Co-allocation to overlapping dendritic branches in the retrosplenial cortex integrates contextual memories across time". bioRχiv. Nov 2021 | DOI: doi.org/10.1101/2021.10.28.466343

Chowdhury A, Luchetti A, Fernandes G, Filho D A, Kastellakis G, Tzilivaki A, Ramirez E, Tran M, Poirazi P, Silva A. "A Locus Coeruleus- dorsal CA1 dopaminergic circuit modulates memory linking". bioRχiv. Oct 2021 | DOI: 10.1101/2021.10.27.466138

Pinitas K, Chavlis S, Poirazi P. "Dendritic Self-Organizing Maps for Continual Learning". arXiv. Oct 2021 | Link: arxiv.org/abs/2110.13611

Acharyaa J, Basu A, Legenstein R, Limbacher T, Poirazi P, Wu X. "Dendritic Computing: Branching Deeper into Machine Learning". Neuroscience. Oct 2021 | DOI: 10.1016/j.neuroscience.2021.10.001

Chavlis S, Poirazi P. "Drawing inspiration from biological dendrites to empower artificial neural networks". Curr Opin Neurobiol. Oct 2021 | DOI: 10.1016/j.conb.2021.04.007 | Zenodo (Open-Access)

Achakulvisut T, Ruangrong T, Mineault P, Vogels TP, Peters MAK, Poirazi P, Rozell C, Wyble B, Goodman DFM, Kording KP. "Towards Democratizing and Automating Online Conferences: Lessons from the Neuromatch Conferences". Trends Cogn Sci. 16 Feb 2021 | DOI: 10.1016/j.tics.2021.01.007

2020

Geiller T, Vancura V, Terada S, Troullinou E, Chavlis S, Tsagkatakis G, Tsakalides P, Ócsai K, Poirazi P, Rózsa BJ, Losonczy A. "Large-Scale 3D Two-Photon Imaging of Molecularly Identified CA1 Interneuron Dynamics in Behaving Mice". Neuron. 09 Dec 2020 | DOI: 10.1016/j.neuron.2020.09.013

Troullinou E, Tsagkatakis G, Chavlis S, Turi GF, Li W, Losonczy A, Tsakalides P, Poirazi P. "Artificial Neural Networks in Action for an Automated Cell-Type Classification of Biological Neural Networks". IEEE TETCI. 13 October 2020 | DOI: 10.1109/TETCI.2020.3028581​

Bassett DS, Cullen KE, …,Poirazi P, …, Sur M,  Ueda HR. "Reflections on the past two decades of neuroscience". Nat Rev Neurosci. 02 Sep 2020 | DOI:  10.1038/s41583-020-0363-6

Poirazi P, Papoutsi A. "Illuminating dendritic function with computational models". Nat Rev Neurosci. 11 May 2020 | DOI: 10.1038/s41583-020-0301-7

Shuman T, Aharoni D, Cai, DJ, …, Chavlis S, …, Pandi I, …, Poirazi P, Silva AJ, Golshani P. "Breakdown of spatial coding and interneuron synchronization in epileptic mice". Nat Neurosci. 06 Jan 2020 | DOI: 10.1038/s41593-019-0559-0

Gidon A, Zolnik TA, Fidzinski P, Bolduan F, Papoutsi A, Poirazi P, Holtkamp M, Vida I, Larkum ME. "Dendritic action potentials and computation in human layer 2/3 cortical neurons". Science. 03 Jan 2020 | DOI: 10.1126/science.aax6239 [Podcast at Quanta Magazine]

2019

Kastellakis G, Poirazi P. "Synaptic Clustering and Memory Formation". Front Mol Neurosci. 6 Dec 2019 | 10.3389/fnmol.2019.00300

Park J, Papoutsi A, Ash RT, Marin MA, Poirazi P, Smirnakis SM. "Contribution of apical and basal dendrites to orientation encoding in mouse V1 L2/3 pyramidal neurons". Nat Commun. 26 November 2019 | DOI: 10.1038/s41467-019-13029-0

Richards BA, Lillicrap TP, …, Poirazi P, …, Kording KP. "A deep learning framework for neuroscience". Nat Neurosci. 28 Oct 2019 | DOI: 10.1038/s41593-019-0520-2

Tzilivaki A., Kastellakis G., Poirazi P. "Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators". Nat Commun. 2019 Aug 14 | DOI: https://doi.org/10.1038/s41467-019-11537-7
[Abstract] [PDF]

Ebner C, Ledderose J, Zolnik TA, Dominiak SE, Turko P, Papoutsi A, Poirazi P, Eickholt BJ, Vida I, Larkum ME, Sachdev RNS. "Optically Induced Calcium-Dependent Gene Activation and Labeling of Active Neurons Using CaMPARI and Cal-Light". Front Synaptic Neurosci. 2019 May 24 | DOI: https://doi.org/10.3389/fnsyn.2019.00016
[Abstract] [PDF]

Park, J., Papoutsi, A., Ash, R. T., Marin, M. A., Poirazi, P., & Smirnakis, S. M. "Contribution of Apical and Basal Dendrites of L2/3 Pyramidal Neurons to Orientation Encoding in Mouse V1". bioRxiv. 2019. | DOI: https://doi.org/10.1101/566588
[Abstract] [PDF]

Turi G.F., Li W.K., Chavlis S., Pandi I., O’Hare J., Priestley J.B., Grosmark A.D., Liao Z., Ladow M., Zhang J.F., Zemelman B.V., Poirazi P., Losonczy A. "Vasoactive Intestinal Polypeptide-Expressing Interneurons in the Hippocampus Support Goal-Oriented Spatial Learning". Neuron. 2019 Jan 31 | DOI: https://doi.org/10.1016/j.neuron.2019.01.009
[Abstract] [PDF]

Ouares K.A., Filipis L., Tzilivaki A., Poirazi P., Canepari M. "Two distinct sets of Ca2+ and K+ channels are activated at different membrane potentials by the climbing fibre synaptic potential in Purkinje neuron dendrites". J Neurosci. 2019 Jan 10 | doi: 10.1523/JNEUROSCI.2155-18.2018. [Epub ahead of print]
[Abstract] [PDF]

Tzilivaki A., Kastellakis G., Poirazi P. "Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators". bioRxiv. 2019 | doi: 10.1101/251314
[Abstract] [PDF]

2018

Shuman T., Aharoni D., Cai D.J., Lee C.R., Chavlis S., Taxidis J., Flores S.E., Cheng K., Javaherian M., Kaba C.C. and Shtrahman, M. "Breakdown of spatial coding and neural synchronization in epilepsy". bioRxiv. 2018 | DOI: 10.1101/358580
[Abstract] [PDF]

Frank A.C., Huang S., Zhou M., Gdalyahu A., Kastellakis G., Silva T.K., Lu E., Wen X., Poirazi P., Trachtenberg J.T., Silva A.J. "Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory". Nat Commun. 2018 January. | DOI: 10.1038/s41467-017-02751-2
[Abstract] [PDF]

2017

Panayiota Poirazi, George Kastellakis. "…with Love, from Post to Pre". Neuron. 2017 September | DOI: 10.1016/j.neuron.2017.09.022
[Abstract] [PDF]

Bartlett W Mel, Jackie Schiller and Panayiota Poirazi. "Synaptic plasticity in dendrites: complications and coping strategies". Current Opinion in Neurobiology. 2017 May | DOI: 10.1016/j.conb.2017.03.012
[Abstract]

Chavlis S., Poirazi P. "Pattern separation in the Hippocampus through the eyes of computational modeling". Synapse. 2017 Mar 18. | doi: 10.1002/syn.21972. [Epub ahead of print] Review.
[Abstract] [PDF]

Poirazi, P. "The perfect grant and how to get it". Nature. 2017 March | DOI: 10.1038/543151a
[Abstract] [PDF]

Petrantonakis P.C., Poirazi P. "A novel and simple spike sorting implementation". IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2016 Dec. | DOI: 10.1109/TNSRE.2016.2640858
[Abstract]

Danielson, N. B., Turi, G. F., Ladow, M., Chavlis, S., Petrantonakis, P. C., Poirazi, P., & Losonczy, A. "In Vivo Imaging of Dentate Gyrus Mossy Cells in Behaving Mice". Neuron. 2017 Feb. | DOI: http://dx.doi.org/10.1016/j.neuron.2016.12.019
[Abstract] [PDF]

2016

2015

2014

[Abstract] [PDF]

2013

Manioudaki ME and Poirazi P
Modeling regulatory cascades using Artificial Neural Networks: the case of transcriptional regulatory networks shaped during the yeast stress response.
Front. Genet. 4:110. doi: 10.3389/fgene.2013.00110
[Abstract] [PDF]

A. Papoutsi, G. Kastellakis, M. Psarrou, S. Anastasakis, P. Poirazi.
Coding and Decoding with Dendrites
Journal of Physiology-Paris doi:10.1016/j.jphysparis.2013.05.003.
[Abstract]  [PDF]

Romani, A., Marchetti, C., Bianchi, D., Leinekugel, X., Poirazi, P., Migliore, M., Marie, H.
Computational modeling of the effects of amyloid-beta on release probability at hippocampal synapses.
Frontiers in Computational Neuroscience, January 2013; doi: 10.3389/fncom.2013.00001
[Abstract] [PDF]

2012

[Abstract] [PDF]

[Abstract] [PDF]

2011

Gómez González JF, Mel BW, Poirazi P.
Distinguishing Linear vs. Non-Linear Integration in CA1 Radial Oblique Dendrites: It’s about Time.
Frontiers in Computational Neuroscience. 2011 November 14 ;5:44.
[Abstract] [PDF]

Tzamali E, Poirazi P, Tollis IG, Reczko M.
A computational exploration of bacterial metabolic diversity identifying metabolic interactions and growth-efficient strain communities.
BMC Syst Biol. 2011 Oct 18;5:167.
[Abstract] [PDF]

Oulas, A, Karathanassis N., Luloupi, A. and Poirazi, P.
Finding cancer-associated miRNAs: methods and tools
Molecular Biotechnology, DOI: 10.1007/s12033-011-9416-4, June 2011.
[Abstract] [PDF]

2010

Pissadaki E.K., Sidiropoulou K., Reczko M., and Poirazi P.
Encoding of Spatio-temporal Input Characteristics by a CA1 Pyramidal Neuron Model.
PLoS Computational Biology 2010 Dec;6(12): e1001038.
[Abstract] [PDF]

Gkirtzou K, Tsamardinos I, Tsakalides P, Poirazi P.
MatureBayes: a probabilistic algorithm for identifying the mature miRNA within novel precursors.
PLoS One 2010 Aug;5(8). pii: e11843
[Abstract] [PDF]

Shilyansky C, Karlsgodt KH, Cummings DM, Sidiropoulou K, Hardt M, James AS, Ehninger D, Bearden CE, Poirazi P, Jentsch JD, Cannon TD, Levine MS, Silva AJ.
Neurofibromin regulates corticostriatal inhibitory networks during working memory performance.
Proc Natl Acad Sci U S A. 2010 Jul;107(29):13141-6.
[Abstract] [PDF]

2009

Zhou Y, Won J, Karlsson MG, Zhou M, Rogerson T, Balaji J, Neve R, Poirazi P, Silva AJ.
CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala.
Nature Neuroscience 2009 Nov;12(11):1438-43.
[Abstract] [PDF]

Oulas A, Boutla A, Gkirtzou K, Reczko M, Kalantidis K and Poirazi P
Prediction of novel microRNA genes in cancer-associated genomic regions–a combined computational and experimental approach.
Nucleic Acids Research 2009 Jun;37(10):3276-87.
[Abstract] [PDF]

Oulas A, Reczko M and Poirazi P.
MicroRNAs and Cancer-the search begins!
IEEE Trans Inf Technol Biomed. vol. 13, No 1, pg. 67-77, Jan 2009.
[Abstract] [PDF]

2008

Petalidis LP, Oulas A, Backlund M, Wayland MT, Liu L, Plant K, Happerfield L, Freeman TC, Poirazi P, Collins VP.
Improved grading and survival prediction of human astrocytic brain tumors by artificial
neural network analysis of gene expression microarray data.
Molecular Cancer Therapeutics (on the cover) vol. 7, No 5, pg. 1013-1024, May 2008.
[Abstract] [PDF]

Liebmann L, Karst H, Sidiropoulou K, van Gemert N, Meijer OC, Poirazi P, Joels M.
Differential effects of corticosterone on the slow afterhyperpolarization in the
basolateral amygdala and CA1 region: possible role of calcium channel subunits.
Journal of Neurophysiology vol. 99, No 2, pg. 958-968, Feb. 2008.
[Abstract] [PDF]

2007

Poirazi, P., Leroy, F., Georgalaki, M.D., Aktypis, A., De Vuyst, L., and Tsakalidou, E.
Use of artificial neural networks and a gamma-concept-based approach to model growth of and bacteriocin production
by Streptococcus macedonicus ACA-DC 198 under conditions simulating Kasseri cheese technology.
Applied Environmental Microbiology vol. 73, No 3, pg. 768-776, Feb. 2007.
[Abstract] [PDF]

Pissadaki, E.K. and Poirazi P.
Modulation of excitability in CA1 pyramidal neurons via the interplay of EC and CA3 inputs.
Neurocomputing, Special Issue for CNS 2006, vol. 70, No 11-12, pg. 1735-1740, June 2007.
[Abstract] [PDF]

Sidiropoulou K., Joels M., and Poirazi P.
Modeling stress-induced adaptations in Ca++ dynamics.
Neurocomputing, Special Issue for CNS 2006, vol. 70, No 11-12, pg. 1640-1644, June 2007.
[Abstract] [PDF]

2006

Pavlidis P. and Poirazi P.
Individualized markers optimize class prediction of microarray data.
BMC Bioinformatics, vol. 7, pg. 345-359, July 2006.
[Abstract] [PDF]

Sidiropoulou K., Pissadaki E.K., and Poirazi P.
Inside the brain of a neuron.
EMBO Reports, vol. 7, pg. 886-892, September 2006.
[Abstract] [PDF]

2005

Markaki M., Orphanoudakis S. and Poirazi P.
Modelling reduced excitability in aged CA1 neurons as a calcium-dependent process.
Neurocomputing, vol. 65-66, pg. 305-314, June 2005.
[Abstract] [PDF]

2004

Poirazi, P. Neocleous, C., Pattichis, C. and Schizas, C.
Classification Capacity of a Modular Neural Network Implementing Neurally Inspired Architecture and Training.
IEEE Transactions in Neural Networks, vol 15, No. 3, pg. 597-612, May 2004.
[Abstract] [PDF]

2003

Poirazi, P. Brannon, T. and Mel, B.W.
Arithmetic of Subthreshold Synaptic Summation in a Model CA1 Pyramidal Cell.
Neuron, vol 37, pg. 977-987, March 2003.
[Abstract] [PDF]

Poirazi, P. Brannon, T. and Mel, B.W.
Pyramidal Neuron as 2-Layer Neural Network.
Neuron, vol 37, pg. 989-999, March 2003.
[Abstract] [PDF]

Poirazi, P. Brannon, T. and Mel, B.W.
About the Model (online supplement)
Neuron, vol 37, pg. 988, March 2003.
[PDF]

1999-2001

Poirazi, P. and Mel, B.W.
Impact of Active Dendritic Processing and Structural Plasticity on Learning and Memory.
Neuron, vol 29, pg. 779-796, March 2001.
[Abstract] [PDF]

Poirazi, P. and Mel, B.W.
Choice and value flexibility jointly contribute to the capacity of a subsampled quadratic classifier.
Neural Computation, vol. 12, num. 5, pg. 1189-1207, 2000.
[Abstract] [PDF]

Poirazi, P. and Mel, B.W.
Towards the Memory Capacity of Neurons with Active Dendrites.
Neurocomputing, vol. 26-27, pg. 237-245, 1999.
[Abstract] [PDF]