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    Publications

    Selected Publications

    1. Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, Zacharioudaki V, Margioris AN, Tsichlis PN, Tsatsanis C. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity. 2009 Aug 21;31(2):220-31 (indexed as ‘Highly cited paper’-ISI)

    2. Zacharioudaki V, Androulidaki A, Arranz A, Margioris AN and Tsatsanis C. Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M. J. Immunol. 2009 182(10):6444-51

    3. Arranz A., Doxaki C., Vergadi E.,  Martinez Y., Vaporidi K., Vanihaki M., Lagoudaki E., Stathopoulos E., Margioris A., Tsichlis PN and Tsatsanis C. Akt1 and Akt2 differentially contribute to macrophage polarization. Proc. Natl. Acad. Sci. USA, 2012 109(24):9517-22
     
    4. Karakasilioti I, Kamileri I, Chatzinikolaou G, Kosteas T, Vergadi E, Robinson AR, Tsamardinos I, Rozgaja TA, Siakouli S, Tsatsanis C, Niedernhofer LJ, Garinis GA. DNA damage triggers a chronic auto-inflammatory response leading to fat depletion in NER progeria. Cell Metab. 2013, 18(3):403-15
     
    5. E. Vergadi, K Vaporidi, E Theodorakis, C Doxaki, E Lagoudaki, E Ieronymaki, V I. Alexaki, M Helms, E Kondili, B Soennichsen, E N. Stathopoulos, A N. Margioris; D Georgopoulos and C Tsatsanis Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction J. Immunol. 2014;192(1):394-406

    6. Doxaki C, Kampranis SC, Eliopoulos AG, Spilianakis C and C. Tsatsanis. Coordinated Regulation of miR-155 and miR-146a Genes during Induction of Endotoxin Tolerance in Macrophages. J Immunol. 2015 Dec 15;195(12):5750-61

    7. Vergadi E, Ieronymaki E, Lyroni K, Vaporidi K, Tsatsanis C. Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization. J Immunol. 2017 Feb 1;198(3):1006-1014. (indexed as ‘Highly cited paper’-ISI)

    8. Lyroni K, Patsalos A, Daskalaki MG, Doxaki C, Soennichsen B, Helms M, Liapis I, Zacharioudaki V, Kampranis SC, Tsatsanis C. Epigenetic and Transcriptional Regulation of IRAK-M Expression in Macrophages. J Immunol. 2017 Feb 1;198(3):1297-1307.

    9. Silva MC, Davoli-Ferreira M, Medina TS, Sesti-Costa R, Silva GK, Lopes CD, Cardozo LE, Gava FN, Lyroni K, Dias FC, Frade AF, Baron M, Nakaya HI, Figueiredo F, Alves-Filho JC, Cunha FQ, Tsatsanis C, Chevillard C, Cunha-Neto E, Hirsch E, Silva JS, Cunha TM. Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nat Commun. 2018 Apr 17;9(1):1513.
     
    10. Alexaki VI, Fodelianaki G, Neuwirth A, Mund C, Kourgiantaki A, Ieronimaki E, Lyroni K, Troullinaki M, Fujii C, Kanczkowski W, Ziogas A, Peitzsch M, Grossklaus S, Sönnichsen B, Gravanis A, Bornstein SR, Charalampopoulos I, Tsatsanis C, Chavakis T. DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway. Mol Psychiatry. 2018 Jun;23(6):1410-1420

    11. Vergadi E, Vaporidi K, Tsatsanis C. Regulation of Endotoxin Tolerance and Compensatory Anti-inflammatory Response Syndrome by Non-coding RNAs. Front Immunol. 2018 Nov 20;9:2705.

    12. Daskalaki MG, Vyrla D, Harizani M, Doxaki C, Eliopoulos AG, Roussis V, Ioannou E, Tsatsanis C, Kampranis SC. Neorogioltriol and Related Diterpenes from the Red Alga Laurencia Inhibit Inflammatory Bowel Disease in Mice by Suppressing M1 and Promoting M2-Like Macrophage Responses. Mar Drugs. 2019 Feb 2;17(2). pii: E97

    13. Ieronymaki E, Theodorakis EM, Lyroni K, Vergadi E, Lagoudaki E, Al-Qahtani A, Aznaourova M, Neofotistou-Themeli E, Eliopoulos AG, Vaporidi K, Tsatsanis C. Insulin Resistance in Macrophages Alters Their Metabolism and Promotes an M2-Like Phenotype. J Immunol. 2019 Mar 15; 202(6):1786-1797.

    14. Ieronymaki E, Daskalaki MG, Lyroni K, Tsatsanis C. Insulin Signaling and Insulin Resistance Facilitate Trained Immunity in Macrophages Through Metabolic and Epigenetic Changes. Front Immunol. 2019 Jun 12;10:1330.