IMBB Researchers developed novel 3D culture systems to study neuronal regeneration.
[Pubmed] [Press Release]
IMBB Researchers in collaboration with colleagues at Los Angeles, San Diego and New York demonstrate that epilepsy-induced deficits in spatial coding are caused by the de-synchronization of interneuronal populations.
[Pubmed] [Press Release]
IMBB Researchers identified a novel mechanism by which irreparable DNA damage induces chronic inflammation and tissue pathology.
[Pubmed] [Press Release]
IMBB researchers, in collaboration with the Smirnakis lab at Harvard Medical School, reveal how dendrites contribute to the orientation tuning of pyramidal neurons in the visual cortex of mice.
[Pubmed]
IMBB Researchers in collaboration with colleagues from Univ. of Geneva, Univ. of Crete and BRFAA discovered and validated distinct gene signatures conferring susceptibility and predicting the severity of Systemic Lupus Erythematosus. This landmark study identifies novel targets for personalized care.
[Pubmed]
In a new study published in Nature Communications, IMBB researchers provide a novel view of dendritic integration of interneurons and their role in brain function.
[Pubmed] [Press release]
IMBB Researchers uncover a link between mitochondrial maturation and germ cell differentiation.
[Pubmed] [Press release]
IMBB Researchers identify a novel function of insulators in transcription regulation.
[Pubmed] [Press release]
Collaboration between researchers at NIH-USA, University of Oslo and IMBB-FORTH revealed the critical role of impaired mitophagy in Altzheimer's Disease pathogenesis.
[Pubmed] [Press release]
By combining experiments with models, this study is the first to show that VIP cells underlie the ability of mice to learn the spatial location of a reward.
[Pubmed] [Press release]
IMBB researchers identify mRNA processing bodies (PBs) as crucial regulators of proteostasis in C. elegans. The study reveals the mechanism for PB-promoted stress resistance and longevity.
[Pubmed] [Press release]
In a new study published in Nature Communications, IMBB-FORTH Researchers uncover the important role of iron regulation inside macrophages in host defense against airborne filamentous fungi.
[Pubmed] [Press release]
In a new study published in Nature Microbiology, IMBB-FORTH Researchers reveal a novel mechanism of melanin-dependent inhibition of calcium signaling during phagocytosis.
[Pubmed] [Press release]
Collaboration between IMBB-FORTH researchers and scientists in Paris uncovers aspirin as a caloric restriction mimetic.
[Pubmed] [Press release]
IMBB and UCLA researchers show how synaptic turnover facilitates learning and memory.
[Pubmed] [Press release] [F1000]
Μελέτη από το εργαστήριο του Καθ. Νεκτάριου Ταβερναράκη αποκαλύπτει πώς το διατροφικό στρες επηρεάζει την μνήμη και την μάθηση μέσω διαφορικής ρύθμισης της αυτοφαγίας σε διαφορετικές περιοχές του εγκεφάλου και διακρίνει την νευροτροφίνη BDNF ως έναν νέο ρυθμιστή της αυτοφαγίας στον εγκέφαλο.
Μελέτη από το εργαστήριο του Καθ. Γιώργου Γαρίνη αποκαλύπτει ότι πρωτεΐνες που επιδιορθώνουν DNA βλάβες παίζουν ενεργό ρόλο στη διαδικασία της ανάπτυξης των θηλαστικών.
Μελέτη από το εργαστήριο του Καθ. Νεκτάριου Ταβερναράκη αποκαλύπτει ένα κομβικό μονοπάτι μοριακής σηματοδότησης που συντονίζει τη δημιουργία και, ταυτόχρονα, την καταστροφή των μιτοχονδρίων στα κύτταρα, κατά τη γήρανση, καθορίζοντας τη διάρκεια ζωής.
Μελέτη από το εργαστήριο του Καθ. Χαράλαμπου Σπηλιανάκη προτείνει ένα νέο μηχανισμό δράσης των μη-κωδικών RNAs στη ρύθμιση της τοπολογίας γονιδίων και του αλληλικού προτύπου έκφρασής τους.