IMBB

Molecular Biology of Unicellular Organisms Group


Selected Publications

  1. Georgakopoulos T. and Thireos, G. (1992) Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription. EMBO J (In press).

  2. Georgatsou, E., Georgakopoulos, T. and Thireos, G. (1992) Cloning of an essential gene encoding a proteasomal subunit in yeast. FEBS Letters 299: 39-43.

  3. Oliver, S.G., ...Alexandraki, D., ...Galland, P., ...Thireos, G., Tzermia, M, ...and Sgouros, J.G. (1992) The complete DNA sequence of yeast chromosome III. Nature 357: 38-46.

  4. Tzamarias, D., Pu, S.W. and Struhl, K. (1992) Mutations in the bZIP domain of Yeast Gcn4 that alter the DNA-binding specificity. Proc. Natl. Acad. Sci. USA 89: 2007-2011.

  5. Kafetzopoulos, D., Thireos, G., Vournakis, J.N. and Bouriotis, V. (1993) The primary structure of a fungal chitin deacetylase reveals the function for two bacterial gene products. Proc Natl Acad Sci USA 90: 8005-8008.

  6. Kim, J., Tzamarias, D., Ellenberger, T., Harison, S. and Struhl, K. (1993) Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZip proteins. Proc Natl Acad Sci USA 90: 4513-4517.

  7. Alexandraki, D and Tzermia, M. (1994) Sequencing of a 13.2 kb segment next to the left telomere of yeast chromosome XI revealed five open reading frames and recent recombination events with the right arms of chromosomes III and V. Yeast 10: S81-S91.

  8. Dialynas, G. and Thireos, G. (1994) Genetic and biochemical evidence for yeast GCN2 protein kinase polymerization. Gene 143: 21- 27.

  9. Dujon, B., ...Alexandraki, D., ...Horaitis, O., ...Tzermia, M., ...and Mewes, H. W. (1994) The complete DNA sequence of chromosome XI of Saccharomyces cerevisiae (666 kb), Nature 369: 371-378.

  10. Georgatsou E. and Alexandraki D. (1994) Two distinctly regulated genes are required for ferric reduction, the first step of iron uptake in Saccharomyces cerevisiae. Molec Cell Biol 14: 3065-3073.

  11. Tzamarias, D. and Struhl, K. (1994) Functional dissection of the Cyc8-Tup1 transcriptional corepressor complex in yeast. Nature 369: 758-761.

  12. Tzermia, M. Horaitis, O. and Alexandraki, D. (1994) The complete sequencing of a 24.6 kb segment of yeast chromosome XI identified the known Loci URA1, SAC1 and TRP3, and revealed 6 new open reading frames including homologues to the threonine dehydratases, membrane transporters, hydantoinases and the phospholipase A2-activating protein. Yeast 10: 663-679.

  13. Tzamarias, D. and Struhl, K. (1994). Functional dissection of the Cyc8-Tup1 transcriptional co-repressor complex in yeast. Nature, 369: 758-761.

  14. Tzamarias, D. and Struhl, K. (1994) Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 co-repressor complex to differentially regulated promoters. Genes and Devel. 9: 821-831.

  15. Georgakopoulos, T., Gounalaki, N. and Thireos, G. (1995) Genetic evidence for the interaction of the yeast GCN5 and ADA2 transcriptional co-activator proteins. Mol Gen Genet 246: 723-728.

  16. Kyrpides N., Papamatheakis S., Tavernarakis N. and Thireos, G. (1995) A transient GCN4 mRNA destabilization follows GCN4 translational derepression. J Biol Chem (In press).

  17. Tavernarakis N. and Thireos G. (1995) A recombinatorial method useful for cloning dominant alleles in Saccharomyces cerevisiae. Nucl Acids Res 23: 537-538.

  18. Tavernarakis N. and Thireos, G. (1995) Transcriptional interference by GCN4 overexpression reveals multiple interactions mediating transcriptional activation. Molec Gen Genet (In press).

  19. Tzamarias, D. and Struhl, K. (1995). Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 co-repressor complex to differentially regulated promoters. Genes and Development, 9: 821-831.N.B. The publications #5 and 16 have also been listed in the Enzyme Technology Group and the Mammalian Molecular Biology Section respectively.

  20. Katsoulou, C., Tzermia, M., Tavernarakis, N. and Alexandraki, D. Sequence analysis of 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI. Yeast (In press).

  21. Galibert, F., Alexandraki, D., Katsoulou, C., Tzermia and Karpfinger-Hartl, L. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. EMBO J. (In press).

  22. Economou, A. and Wickner, W. (1994) SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertion. Cell 78, 835-843.

  23. Economou, A. , Pogliano,J.P., Beckwith, J., Oliver, D.B. and Wickner, W. (1995) SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF. Cell 83 , 1171-1181.

  24. Price, A., Economou, A., Duong, F. and Wickner, W.(1996) Separable ATPase and membrane insertion domains of the SecA subunit of preprotein translocase. Journal of Biological Chemistry 271, 31580-31584.