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Το Ινστιτούτο Μοριακής Βιολογίας και Βιοτεχνολογίας (ΙΜΒΒ) έχει έδρα το Ηράκλειο (Κρήτη), και διεξάγει βασική και εφαρμοσμένη έρευνα σε καθιερωμένες και αναδυόμενες περιοχές της Bιοϊατρικής επιστήμης. To ΙΜΒΒ ιδρύθηκε το 1983 και αποτελεί τμήμα του Ιδρύματος Τεχνολογίας και Έρευνας (ΙΤΕ), ένα από τα μεγαλύτερα ερευνητικά κέντρα στην Ελλάδα. Η έρευνα στο ΙΜΒΒ είναι ποικίλη και εμπίπτει στις ακόλουθες περιοχές: Γονιδιακή Ρύθμιση, Εξελικτική Γενετική, Νευροεπιστήμες, Αλληλεπιδράσεις μεταξύ παθογόνων και ξενιστών και Ανοσία, Δομή και Λειτουργία Πρωτεϊνών.
Νέα
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IMBB researchers uncover a novel molecular mechanism for Nucleotide Excision Repair during mammalian development. Kamileri et al reveal that key proteins in this pathway activate the transcription of genes involved in mammalian growth. |
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IMBB researchers uncover a novel, unexpected molecular mechanism required for the degeneration of nerve cells. Troullinaki and Tavernarakis reveal that two processes normally essential for cell survival, endocytosis and intracellular trafficking, also contribute to necrotic cell death. |
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The Economou lab in collaboration with the Kalodimos lab (Rutgers U.) reveal a novel regulatory mechanism in protein-protein interactions. Chen et al show that the interaction of a chaperone with its substrate is mediated by finely tuned structural instability and is coupled to molecular mimicry. |
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IMBB researchers contribute to the unraveling of the molecular mechanism of Notch signalling. Daskalaki et al show that ubiquitylation of the Notch ligand Delta simultaneously triggers its endocytosis and its signalling activity. |
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Development and Evolution lab publishes iTRAC, a method for exploiting gene-traps in established and emerging model organisms. Kontarakis et al demonstrate iTRAC in the crustacean Parhyale |
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A novel mechanism of mitochondria biogenesis |
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A novel mechanism regulating metabolism and ageing |
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A novel mechanism that controls protein secretion |
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The structural basis of the interaction of signal peptides with the translocase |









