Publications

Amsen D, Spilianakis CG, Flavell RA. How are T(H)1 and T(H)2 effector cells made? Curr. Opin.Immunol. 2009, 2: 153-60.

Brown MR, Kronengold J, Gazula VR, Spilianakis CG, Flavell RA, von Hehn CA, Bhattacharjee A, Kaczmarek LK. Amino-termini isoforms of the Slack K+ channel, regulated by alternative promoters, differentially modulate rhythmic firing and adaptation. J Physiol. 2008 , 586(Pt 21):5161-79.

Town T, Breunig JJ, Sarkisian MR, Spilianakis CG, Ayoub AE, Liu X, Ferrandino AF, Gallagher AR, Li MO, Rakic P, Flavell RA. The stumpy gene is required for mammalian ciliogenesis. Proc Natl Acad Sci U S A. 2008, 105(8):2853-8.

Spilianakis C.G, Flavell R.A. Epigenetic regulation of Ifng expression. Nat Immunol. 2007, 8:681-3.

Spilianakis C.G. , Flavell R.A. Molecular biology. Managing associations between different chromosomes. Science . 2006, 312:207-8.

Lee G.R., Kim S.T., Spilianakis C.G. , Fields P.E., Flavell R.A. T helper cell differentiation: Regulation by cis-elements and epigenetics. Immunity .2006,4:369-79.

Gialitakis M., Kretsovali A., Spilianakis C.G. , Kravariti, L., Mages J., Hoffmann R., Hatzopoulos A.K., Papamatheakis J. Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. Nucleic Acids Res. 2006, 34:765-72.

Spilianakis C.G. , Lee G.R., Flavell R.A. Twisting the Th1/Th2 immune response via the retinoid X receptor: Lessons from a genetic approach. Eur J Immunol. 2005, 35:3400-4.

Spilianakis C.G., Lalioti M., Town T., Lee GR., Flavell RA. Interchromosomal associations between alternatively expressed loci. Nature ( Research Article ). 2005, 435:637-645.

Lee GR, Spilianakis C.G. , Flavell RA. Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions. Nat Immunol. 2005, 6:42-8.

Spilianakis C.G. , Flavell RA. Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat Immunol. 2004, 5:1017-27.

Muhlethaler-Mottet A., Krawczyk M., Masternak K., Spilianakis C.G. , Kretsovali A., Papamatheakis J., Reith W. The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA. J Biol Chem. 2004, 279:40529-35.

Spilianakis C.G. , Kretsovali A., Agalioti T., Makatounakis T., Thanos D., Papamatheakis J. CIITA regulates transcription onset viaSer5-phosphorylation of RNA Pol II. EMBO J. 2003, 22:5125-36.

Tzortzakaki E., Spilianakis C.G. , Zika E., Kretsovali A., Papamatheakis J. Steroid receptor coactivator 1 links the steroid and interferon gamma response pathways. Mol Endocrinol. 2003, 12:2509-18.

Spilianakis C.G. , Kretsovali A., Dimakopoulos A., Makatounakis T., Papamatheakis J. Self-association of class II transactivator correlates with its intracellular localization and transactivation. J Biol Chem. 2001, 276:32191-7.

Spilianakis C , Papamatheakis J, Kretsovali A. Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes. Mol Cell Biol. 2000, 20:8489-98.

Kretsovali A., Agalioti T., Spilianakis C.G. , Tzortzakaki E., Merika M., Papamatheakis J. Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator. Mol Cell Biol. 1998, 18:6777-83.