Welcome to the web site of the Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas (IMBB-FORTH). IMBB is one of the most prominent life science research institutions in Greece, with an outstanding record of scientific achievements, state of the art infrastructure and a broad range of research, innovation and educational activities. IMBB’s main mission is to pursue cutting-edge research and promote scientific excellence.
Highlights
Seed longevity is controlled by metacaspases
IMBB researchers uncover the crucial role of a novel proteolytic pathway with metacaspases in maintaining protein homeostasis and lipid droplet function in seeds, processes which are vital for their longevity. Understanding these molecular mechanisms, could lead to enhanced seed longevity, which is crucial for food security and biodiversity conservation.
Spermidine is vital for inducing autophagy and extending longevity during intermittent fasting
An international scientific collaboration between IMBB researchers, scientists from Paris Cité University in France, and the University of Graz in Austria reveals the conserved role of spermidine in regulating autophagy and extending lifespan during intermittent fasting.
Endonucleosis mediates internalization of cytoplasm into the nucleus
IMBB Researchers identified novel cellular survival mechanisms involving hyperploidization and endonucleosis, a membrane assisted internalization of cytoplasm into the nucleus. These cellular actions control genome instability caused by defective epigenetic regulation.
Reproductive status regulates the mitochondrial stress response
International collaboration between researchers at IMBB and University of Cologne reveals that germline reproductive signals impact the ability of somatic tissues to induce the mitochondrial unfolded protein response, highlighting the decline in reproductive capacity as a primary cause of proteostasis collapse that occurs during ageing.
News
Seed longevity is controlled by metacaspases
August 27. 2024
In the quest to understand how seeds can survive extreme desiccation and remain viable for millennia, researchers at IMBB led by Professor Panagiotis Moschou have uncovered the crucial role of type II metacaspases (MCA-IIs), in maintaining seed longevity. Seeds usually remain dry in an idle state by accumulating protective proteins and lipids...
Prestigious H.F.R.I. – SNF grant “Always strive for excellence – Theodoros Papazoglou” to IMBB researcher
August 21. 2024
The group of Dr. Yiota Poirazi, Director of Research at the Institute of Molecular Biology and Biotechnology of FORTH, was awarded a prestigious grant co-funded by the Stavros Niarchos Foundation (SNF) and the Hellenic Foundation for Research and Innovation (H.F.R.I.) under the 5th Call of “Science and Society” Action “Always strive for excellence – Theodoros Papazoglou”...
International scientific collaboration reveals how intermittent fasting regulates ageing through autophagy
August 08. 2024
Recent research at the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology-Hellas (FORTH), at the Paris Cité University, and at the University of Graz, published today in the premier international science periodical Nature Cell Biology, sheds light on the mechanism through which spermidine regulates autophagy, a process that ensures the recycling of components within the cell, to promote the anti-ageing effects of intermittent fasting.
International workshop “Vector Control: Insecticides and Beyond” at IMBB
July 11-12. 2024
The two-day workshop was held at IMBB, Heraklion on July 11-12. The meeting was organized by the ERA Chair MicroBioPest programme and brought together highly distinguished speakers from the USA and UK. Notably four of those are IMBB Alumni: George Dimopoulos, Professor at Johns Hopkins USA, Professor Laurence J. Zwiebel, Vanderbilt University, USA...
Events
"Ribosomal Proteins in Neuroinflammation: Advanced Insights from Translatome Studies”
IMBB Seminar
Srivathsa S Magadi
IMBB Alumnus Postdoctoral Fellow
Department of Biomedical and Clinical Sciences (BKV)
Linköping University
Date: August 2, 2024 @ 13:00
Location: Seminar Room 1 "Kostas Fotakis", FORTH’s bldg
Host: C. Delidakis
Attached file: Abstract & Biosketch
"A Less Artificial Intelligence"
IMBB Seminar
Prof. Andreas TOLIAS
Department of Ophthalmology,
Byers Eye Institute, Stanford Bio-X
Wu Tsai Neurosciences Institute
Human-Centered Artificial Intelligence Institute
Department of Electrical Engineering
Stanford University, Stanford, CA 94304, USA
Date: July 31, 2024 @ 16:00
Location: Seminar Room 1 "Kostas Fotakis", FORTH’s bldg
Attached file: Biosketch
Host: E. Froudarakis
Partnerships - Spin offs - Links
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