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  • Structural-Biology
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  • Cellular & Developmental Biology and Biology
  • Gene Regulation & Epigenetics
  • InfectionsImmunity
  • Plant Molecular Biology
  • Ancient DNA & Population Genetics 2
  • Bioinformatics
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About IMBB

Welcome to the web site of the Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas (IMBB-FORTH). IMBB is one of the most prominent life science research institutions in Greece, with an outstanding record of scientific achievements, state of the art infrastructure and a broad range of research, innovation and educational activities. IMBB’s main mission is to pursue cutting-edge research and promote scientific excellence.

 

Highlights

Pathogenic bacteria inhibit host cell secretion to manipulate host immunity

Pathogenic bacteria inhibit host cell secretion to manipulate host immunity

This study revealed a hitherto unknown strategy of economically important pathogenic bacteria of Xanthomonas genus, which use a specific virulence protein (effector) that interferes with the assembly of the exocyst protein complex, in order to inhibit the exocyst-dependent secretion mechanism of the host cells.

Reduction of mitochondrial mass extends lifespan and protects against glucotoxicity

Reduction of mitochondrial mass extends lifespan and protects against glucotoxicity

Interdisciplinary scientific collaboration between the Institute of Molecular Biology and Biotechnology (IMBB, FORTH), and the Institute of Chemical Engineering Sciences (ICE-HT, FORTH), sheds light onto the interplay between metabolism and the rate of ageing.

Tweets

 

IL-33-decorated neutrophil extracellular traps promote IFNα production in SLE

IL-33-decorated neutrophil extracellular traps promote IFNα production in SLE

Work by the Laboratory of Rheumatology, Autoimmunity and Inflammation demonstrates neutrophil extracellular traps (NETs) decorated with bioactive IL-33 in the blood and inflamed tissues of patients with Systemic Lupus Erythematosus (SLE). IL-33-decorated NETs induce IFNα synthesis by plasmatocytoid dendritic cells through the ST2L receptor.

Structural dynamics in the evolution of a bilobed protein scaffold

Structural dynamics in the evolution of a bilobed protein scaffold

International collaboration between IMBB-FORTH and the Ludwig Maximilian University of Munich (Germany), with the contribution of researchers from the Universities of Groningen (The Netherlands) and Leuven (Belgium) shaded light on the role of Structural Dynamics in protein evolvability.

Events

October 7th, 2022 @ 18:30 - 20:30
2022 Kafatos Lectures
“Evolution and Embryonic Development: The Complex Story of our Dual Origins”
Speaker: Denis Duboule (He is a Professor at the École polytechnique fédérale de Lausanne (EPFL) and the Collège de France, and was a Group Leader at EMBL Heidelberg from 1988-1993.)
[Registration: link]
[Location: 'Cultural Conference Center of Heraklion' ]
October 12 @ 15:00 - 16:00
Joint Seminar Series in Translational and Clinical Medicine:
UoC Medical School – IMBB-FORTH – UCRC
“Microbiome: From Basic Research to Clinical Practice”
Speaker: Lagouvardos Elias (Leader of Research Group "Microbial Bioinformatics" , Technische Universität München and Fellow Researcher IMBB-FORTH )
[Location: online]
October 14th 2022 @ 12:00
IMBB SEMINAR
“Directly observing protein molecules in dynamic action by high-speed atomic force microscopy”
Speaker: Prof. Toshio ANDO (Nano Life Science Institute (WPI-NanoLSI), Kanazawa University Kakuma-machi, Kanazawa 920-1192, Japan )
[Host: E. Gizeli ]
[Location: “Seminar Room 1”, FORTH’s bldg ]

News

July 29. 2022
Professor Christos Louis honored for contributions to malaria mosquito biology [More]
July 14. 2022
«13th Scientific Retreat», of the Foundation for Research & Technology - Hellas (FORTH) [Press Release]
June 1. 2022
Pathogenic bacteria inhibit host cell secretion to manipulate host immunity. [Press Release] [Plant Cell]
May 11. 2022
IMBB-FORTH mourns the loss of its colleague and former member of the Institute Kyriakos Petratos. [More]
March 30. 2022
Professor Nektarios Tavernarakis elected Chair of the European Institute of Innovation & Technology. [Press Release]
 

Partnership

 UoC - Biology department UoC - School of Medicine  EU Life 

Precision Medicine

Digenia website  EDIMO website