Welcome to the web site of the Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas (IMBB-FORTH). IMBB is one of the most prominent life science research institutions in Greece, with an outstanding record of scientific achievements, state of the art infrastructure and a broad range of research, innovation and educational activities. IMBB’s main mission is to pursue cutting-edge research and promote scientific excellence.
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40 years of IMBB Alumni Reunion event, October 20 2023. Follow the links for event photos, IMBB history posters and IMBB photo posters. IMBB Alumni Community members can view more photos. |
Highlights
Profiling the dynamics of chromatin release of newly transcribed RNA
Transcription and processing of newly transcribed RNA are dynamic processes in the nucleus of human cells. A new study by researchers at IMBB and Helmholtz Center Munich profiled the kinetics of chromatin dissociation of RNA transcripts, and uncover features of long non-coding RNA processing. The results have implications for the design of effective RNA-based therapeutics.
Caloric restriction mimetic enhances remyelination by promoting a less inflammatory environment
IMBB researchers showed that NAM, a form of vitamin B3, can enhance myelin production after demyelination by signaling to microglia to stop causing myelin damage and to astrocytes to reduce inflammation. NAM is an FDA-approved caloric restriction mimetic that induces autophagy
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Unlocking the Potential of PML: A Defender Against Breast Cancer Metastasis
PML is a protein that regulates important cellular decisions about life or death. A new study by IMBB researchers proposes that PML is a breast - tumor suppressor and can serve as a new biomarker. They found that PML limits breast cancer metastasis by inhibiting cancer stem cell survival, tumor cell migration and blood vessel formation.
A transporter in mosquito legs acts like a pump, exporting insecticide out of the organism
Anopheles mosquitoes transmit malaria, exerting a tremendous public health burden, with the control heavily relying on insecticides. A new study published by IMBB researchers shows that a transporter, found in mosquito legs can remove the insecticide out of the organism acting like a pump.This mechanism could be targeted to restore insecticide toxicity.
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