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About IMBB

Welcome to the web site of the Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas (IMBB-FORTH). IMBB is one of the most prominent life science research institutions in Greece, with an outstanding record of scientific achievements, state of the art infrastructure and a broad range of research, innovation and educational activities. IMBB’s main mission is to pursue cutting-edge research and promote scientific excellence.

 

Highlights

Transcription stress leads to paracrine senescence

Transcription stress leads to paracrine senescence

IMBB researchers discovered that transcription stress at telomeres triggers the release of telomeric DNA fragments in the cytoplasm leading to a viral-like response and paracrine senescence.

DNA damage in microglia leads to neurodegeneration

DNA damage in microglia leads to neurodegeneration

IMBB researchers discovered DNA damage triggers cytosolic DNA buildup in microglia, provoking an immune reaction in mouse brain that triggers neuronal cell death. IMBB researchers devised an anti-inflammatory method to target microglia, remove cytosolic DNAs, and delay neurodegeneration onset.

 

 

Polycomb-mediated silencing of miR-8 is required for maintenance of intestinal stemness in Drosophila melanogaster

Polycomb-mediated silencing of miR-8 is required for maintenance of intestinal stemness in Drosophila melanogaster

IMBB researchers showed that the balance between intestinal stem cell renewal and differentiation is regulated epigenetically by a dynamic interplay between Polycomb Repressive Complex 2 (PRC2), the microRNA miR-8 and Notch signaling, that holds implications for treating intestinal diseases.

Detection of isothermally-amplified DNA by naked-eye observation

Detection of isothermally-amplified DNA by naked-eye observation

Work carried out in Biosensors lab demonstrates a novel method to detect isothermally amplified nucleic acids through naked-eye observation, utilizing chitosan-capped AuNPs. This work impacts global diagnostics through the demonstration of an instrument-free detection method, suitable for PoCT.

 

News

The story "An iron armor against fungal pathogens" for the research of Giorgos Chamilos group in IMBB is featured in the European "Research Matters" campaign

The story "An iron armor against fungal pathogens" for the research of Giorgos Chamilos group in IMBB is featured in the European "Research Matters" campaign

May 13. 2024

The work of George Chamilos’ group at IMBB, on fighting infectious fungal diseases is featured at Research Matters. The Research Matters campaign is an initiative among European universities, research institutes, funding agencies, industry partners and communication professionals across Europe that aims to showcase that research is vital in shaping our future and addressing global challenges, and advocate for increased investment in research.

 

[Press Release]

Greek researchers from FORTH, NKUA and Harvard University reveal a new mechanism that regulates intestinal stem cells

Greek researchers from FORTH, NKUA and Harvard University reveal a new mechanism that regulates intestinal stem cells

March 7. 2024

Adult stem cells have attracted great scientific interest because of their ability to self-renew and differentiate into other cell types. In an article published recently at the high-impact journal Nature Communications, researchers from the National Kapodistrian University of Athens (NKUA), the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology-Hellas (FORTH), and Harvard University, led by Prof. Aristides Eliopoulos of NKUA and postdoctoral researcher Dr. Zoe Veneti of FORTH-IMBB, reveal a new mechanism that regulates the proliferation and differentiation of intestinal stem cells.

[Press Release]

Prestigious ERC Consolidator Grant awarded to IMBB-FORTH Researcher Dr. Panagiotis N. Moschou

Prestigious ERC Consolidator Grant awarded to IMBB-FORTH Researcher Dr. Panagiotis N. Moschou

January 31. 2024

Panagiotis N. Moschou, Researcher at the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology – Hellas (FORTH) and Associate Professor at the Department of Biology, University of Crete is awarded a Consolidator Grant from the European Research Council (ERC). The ERC Consolidator Grants are awarded to outstanding researchers of any nationality and age, with a scientific track record showing great promise. Panagiotis N. Moschou, who works at the interface of cell biology and molecular physiology will receive €1.9 million 

[Press Release]

40 years IMBB Alumni Community Reunion October 20

40 years IMBB Alumni Community Reunion October 20

November 3. 2023

The 40 years celebration of IMBB and the First IMBB Alumni Community Reunion successfully took place on October 20. An enthusiastic audience of more than 100 alumni on site as well as another 50 on zoom together with present members of IMBB listened to scientific talks as well as personal memories from IMBB alumni. A poster session gave everyone the opportunity to present their work, whether in the academic or private sector. In the evening we all gathered for dinner and dancing with our special DJ playing.

[More]

 

Events

"Rewiring of lipid metabolism upon sensing of fungal melanin is an essential host defense mechanism in alveolar macrophages"

IMBB Colloquium

Vassilis NIDRIS
PhD candidate
Chamilos lab
Date: May 31, 2024 @ 13:00
Location: “Seminar Room 1 "Kostas Fotakis”, FORTH’s bldg

"Saccharomyces variation across the world"

IMBB Seminar

Gianni LITTI
Senior CNRS Researcher
Institute for Research on Cancer and Ageing of Nice (IRCAN)
France
Date: May 28, 2024 @ 13:00
Location: Seminar Room 1 "Kostas Fotakis", FORTH’s bldg
Abstract & Biosketch | Poster
Host: A. Pittis

"Ask the ancestors: resurrecting and re-evolving the bacterial flagellar motor"

IMBB Seminar

Matthew BAKER
Scientia Associate Professor,
UNSW Sydney (BABS),
Faculty of Science, Australia
Date: May 27, 2024 @ 14:00
Location: Seminar Room 1 "Kostas Fotakis", FORTH’s bldg
Abstract & Biosketch
Host: G. Gouridis

"Genetics of spontaneous coronary artery dissection: Rare variants and polygenic risk"

IMBB Seminar

Eleni GIANNOULATOU
Head of Computational Genomics Laboratory,
Victor Chang Cardiac Research Institute Associate Professor,
School of Clinical MedicineFaculty of Medicine and Health,
UNSW Sydney Australia
Date: May 27, 2024 @ 15:30
Location: Seminar Room 1 "Kostas Fotakis", FORTH’s bldg
Abstract & Biosketch
Host: M. Lavigne

 

Partnership

 UoC - Biology department UoC - School of Medicine  EU Life 

Precision Medicine

Digenia website  EDIMO website