Welcome to the web site of the Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas (IMBB-FORTH). IMBB is one of the most prominent life science research institutions in Greece, with an outstanding record of scientific achievements, state of the art infrastructure and a broad range of research, innovation and educational activities. IMBB’s main mission is to pursue cutting-edge research and promote scientific excellence.
Remote control of autophagy and metabolism in the liver
In a Preview article published in Cell Metabolism, Prof. Nektarios Tavernarakis discusses a study that delineates a signaling cascade that is mobilized by neurons in the hypothalamus to modulate autophagy and metabolism in the liver.
Revealing the structure and function of a cytoskeletal actin in malaria parasites
Malaria parasites cause malaria, a devastating disease in many poor countries. A study by researchers from IMBB and University of Bergen investigated a parasite specific actin to understand its structure and function. The findings have implications for strategies to control the disease.
ΙΜΒΒ scientists uncovered the molecular mechanisms involved in the pathogenesis of the neurodegenerative disorder Wolfram Syndrome
Recent study at IMBB, published in Cell Death and Disease revealed that CISD-1, an iron sulfur cluster binding protein implicated in the pathogenesis of the neurodegenerative disorder Wolfram Syndrome type 2, modulates longevity and proteostasis by engaging autophagy and the mitochondrial intrinsic apoptosis pathway.
Age-dependent nuclear lipid droplet accumulation is a cellular hallmark of ageing
Interdisciplinary scientific collaboration between the Institute of Molecular Biology and Biotechnology (IMBB, FORTH), the Institute of Electronic Structure and Laser (IESL, FORTH) and the Medical School of National and Kapodistrian University of Athens (NKUA), sheds light into the molecular mechanisms that regulate nuclear lipid droplets accumulation during ageing.
IMBB is organizing an Alumni Reunion event for the celebration of the 40 years of IMBB. The celebration will take place at FORTH premises in Heraklion on Friday October 20, 2023. [More]