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John Vontas

John Vontas

IMBB Group Leader (Professor, Agr. Pharmacology)
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Some of the most acute challenges that the world faces now and in the foreseeable future are caused by insecticide resistant arthropods that seriously threaten human health and food security. Research in my laboratory focusses on the molecular analysis of the mechanisms by which insects develop resistance to insecticides, aiming to develop means of managing and overcoming this resistance. Our approaches include, classical bioassays, omic analyses and genetic / reverse genetic studies, to identify genes and mutations associated with resistance. Advanced molecular diagnostics are developed, and used to measure resistance dynamics and evolution in major disease vectors and agricultural pests. Inhibitors of detoxification enzymes for novel insecticide formulations capable to tackle resistance are developed in collaboration with the Industry. Finally, we explore biotechnology based approaches to identify and characterize novel molecular targets for the control of insect pests and mosquitoes.

Nauen R, Bass C, Feyereisen R, Vontas J. (2021) The Role of Cytochrome P450s in Insect Toxicology and Resistance. Annu Rev Entomol. DOI: 10.1146/annurev-ento-070621-061328. PMID: 34590892 (in press)

Vlogiannitis S, Mavridis K, Dermauw W, Snoeck S, Katsavou E, Morou E, Harizanis P, Swevers L, Hemingway J, Feyereisen R, Van Leeuwen T, Vontas J. (2021) Reduced proinsecticide activation by cytochrome P450 confers coumaphos resistance in the major bee parasite Varroa destructor. Proc Natl Acad Sci U S A. 118:e2020380118.

Ingham VA, Anthousi A, Douris V, Harding NJ, Lycett G, Morris M, Vontas J, Ranson H. (2020) A sensory appendage protein protects malaria vectors from pyrethroids. Nature. 577:376-380.

Vontas J, Grigoraki L, Morgan J, Tsakireli D, Fuseini G, Segura L, Niemczura de Carvahlo J, Nguema R, Weetman D, Slotman MA, Hemingway J. (2018) Rapid selection of a pyrethroid metabolic enzyme CYP9K1 by operational malaria control activities. Proc Natl Acad Sci U S A. 115:4619-4624.

Balabanidou V, Kampouraki A, MacLean M, Blomquist GJ, Tittiger C, Juárez MP, Mijailovsky SJ, Chalepakis G, Anthousi A, Lynd A, Antoine S, Hemingway J, Ranson H, Lycett GJ, Vontas J. (2016) Cytochrome P450 associated with insecticide resistance catalyzes cuticular hydrocarbon production in Anopheles gambiae. Proc Natl Acad Sci U S A. 113:9268-9273.


(211) Troczka BJ, Singh KS, Zimmer CT, Vontas J, Nauen R, Hayward A, Bass C. (2021) Molecular innovations underlying resistance to nicotine and neonicotinoids in the aphid Myzus persicae. Pest Manag Sci. DOI: 10.1002/ps.6558. PMID: 34270160 (in press)

(210) Stavrakaki M, Ilias A, Ioannidis P, Vontas J, Roditakis E. (2021) Investigating mechanisms associated with emamectin benzoate resistance in the tomato borer Tuta absoluta. J Pest Sci. DOI: 10.1007/s10340-021-01448-2. (in press)

(209) Vlogiannitis S, Jonckheere W, Laget D, de Graaf DC, Vontas J, Van Leeuwen T. Pyrethroid target‑site resistance mutations in populations of the honey bee parasite Varroa destructor (Acari: Varroidae) from Flanders, Belgium. Exp. Appl. Acarol. 85:205-221. DOI: 10.1007/s10493-021-00665-9. PMID: 34676469 

(208) Nauen R, Bass C, Feyereisen R, Vontas J. (2021) The Role of Cytochrome P450s in Insect Toxicology and Resistance. Annu Rev Entomol. DOI: 10.1146/annurev-ento-070621-061328. PMID: 34590892 (in press)

(207) Luong HNB, Damijonaitis A, Nauen R, Vontas J, Horstmann S. (2021) Assessing the anti-resistance potential of public health vaporizer formulations and insecticide mixtures with pyre-throids using transgenic Drosophila lines. Parasit Vectors. 14(1):495. DOI: 10.1186/s13071-021-04997-8. PMID: 34565459

(206) Piameu M, Nwane P, Toussile W, Mavridis K, Wipf NC, Kouadio PF, Mbakop LR, Mandeng S, Ekoko WE, Toto JC, Ngaffo KL, Ngo Etounde PK, Ngantchou AT, Chouaibou M, Müller P, Awono-Ambene P, Vontas J, Etang J. (2021) Pyrethroid and Etofenprox Resistance in Anopheles gambiae and Anopheles coluzzii from Vegetable Farms in Yaoundé, Cameroon: Dynamics, Intensity and Molecular Basis. Molecules. 26(18):5543. DOI: 10.3390/molecules26185543. PMID: 34577014

(205) Papadimitriou F, Folia M, Ilias A , Papapetrou P, Roditakis E, Bass C, Vontas J, Margaritopou-los JT. Flupyradifurone resistance in Myzus persicae populations from peach and tobacco in Greece. Pest Manag Sci. DOI: 10.1002/ps.6637. PMID: 34498376 (in press)

(204) Mavridis Κ, Papapostolou ΚΜ, Riga Μ, Ilias Α, Michaelidou Κ, Bass C, Van Leeuwen T, Tsagkarakou A, Vontas J. (2021) Multiple TaqMan qPCR and droplet digital PCR (ddPCR) diagnostics for pesticide resistance monitoring and management, in the major agricultural pest Tetranychus urticae. Pest Manag Sci. DOI: 10.1002/ps.6632. PMID: 34480408 (in press)

(203) Mastrantonio V, Porretta D, Lucchesi V, Güz N, Çagatay NS, Bellini R, Vontas J, Urbanelli S. (2021) Evolution of Adaptive Variation in the Mosquito Culex pipiens: Multiple Independent Origins of Insecticide Resistance Mutations. Insects. 12:676. DOI: 10.3390/insects12080676. PMID: 34442242

(202) Balaska S, Fotakis EA, Chaskopoulou A, Vontas J. (2021) Chemical control and insecticide resistance status of sand fly vectors worldwide. PLoS Negl Trop Dis. 15(8):e0009586. DOI: 10.1371/journal.pntd.0009586. PMID: 34383751

(201) Mavridis K, Michaelidou K, Vontas J. (2021) Highly sensitive droplet digital PCR-based diagnostics for the surveillance of malaria vector populations in low transmission and incipient resistance settings. Expert Rev Mol Diagn. 1-10. DOI: 10.1080/14737159.2021.1963234. PMID: 34328051

(200) Singh KS, Cordeiro EMG, Troczka BJ, Pym A, Mackisack J, Mathers TC, Duarte A, Legeai F, Robin S, Bielza P, Burrack HJ, Charaabi K, Denholm I, Figueroa CC, Ffrench-Constant RH, Jander G, Margaritopoulos JT, Mazzoni E, Nauen R, Ramírez CC, Ren G, Stepanyan I, Umina PA, Voronova NV, Vontas J, Williamson MS, Wilson ACC, Xi-Wu G, Youn YN, Zimmer CT, Simon JC, Hayward A, Bass C. (2021) Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae. Commun Biol. 4(1):847. DOI: 10.1038/s42003-021-02373-x. PMID: 34234279

(199) Fotoukkiaii SM, Wybouw N, Kurlovs A, Tsakireli D., Pergantis SA., Clark RM, Vontas J, Van Leeuwen T (2021) High-resolution genetic mapping reveals cis-regulatory and copy number variation in loci associated with cytochrome P450-mediated detoxification in a generalist arthropod pest. Plos Genet. 17(6): e1009422. DOI: 10.1371/journal.pgen.1009422. PMID: 34153029

(198) İnak E, Özdemir E, Atış AE, Randa Zelyüt F, İnak A, Demir Ü, Roditakis E, Vontas J. (2021) Population structure and insecticide resistance status of Tuta absoluta populations from Turkey. Pest Manag Sci. 77:4741-4748. DOI: 10.1002/ps.6516. PMID: 34151488

(197) Djiappi-Tchamen B, Nana-Ndjangwo MS, Mavridis K, Talipouo A, Nchoutpouen E, Makoudjou I, Bamou R, Paul Mayi AM, Awono-Ambene P, Tchuinkam T, Vontas J, Antonio-Nkondjio C. (2021) Analyses of Insecticide Resistance Genes in Aedes aegypti and Aedes albopictus Mosquito Populations from Cameroon. Genes (Basel). 12(6):828. DOI: 10.3390/genes12060828. PMID: 34071214

(196) Sene NM, Mavridis K, Ndiaye EH, Diagne CT, Gaye A, Ngom EHM, Ba Y, Diallo DJ, Vontas J, Dia I, Diallo M. (2021) Insecticide resistance status and mechanisms in Aedes aegypti popu-lations from Senegal. PLoS Negl Trop Dis. 15(5):e0009393. DOI: 10.1371/journal.pntd.0009393. PMID: 33970904

(195) Diarra RA, Traore MM, Junnila A, Traore SF, Doumbia S, Revay EE, Kravchenko VD, Schlein Y, Arheart KL, Gergely P, Hausmann A, Beck R, Xue RD, Prozorov AM, Kone AS, Majam-bere S, Vontas J, Beier JC, Müller GC. (2021) Testing confgurations of attractive toxic sugar bait (ATSB) stations in Mali, West Africa, for improving the control of malaria parasite transmission by vector mosquitoes and minimizing their effect on non-target insects. Malar J. 20:184. DOI: 10.1186/s12936-021-03704-3. PMID: 33853632

(194) Talipouo A, Mavridis K, Nchoutpouen E, Djiappi-Tchamen B, Fotakis EA, Kopya E, Bamou R, Kekeunou S, Awono-Ambene P, Balabanidou V, Balaska S, Wondji CS, Vontas J, Antonio-Nkondjio C. (2021) High insecticide resistance mediated by different mechanisms in Culex quinquefasciatus populations from the city of Yaoundé, Cameroon. Sci. Reports. 11:7322. DOI:10.1038/s41598-021-86850-7. PMID: 33795804

(193) Livadaras I, Koidou V, Pitsili E, Moustaka J, Vontas J, Siden-Kiamos I. (2021) Stably inherited transfer of the bacterial symbiont Candidatus Erwinia dacicola from wild olive fruit flies Bactrocera oleae to a laboratory strain. Bull Entomol Res. 5:1–6. DOI:10.1017/S0007485321000031. PMID: 33541447

(192) Vlogiannitis S, Mavridis K, Dermauw W, Snoeck S, Katsavou E, Morou E, Harizanis P, Swevers L, Hemingway J, Feyereisen R, Van Leeuwen T, Vontas J. (2021) Reduced proinsecticide activation by cytochrome P450 confers coumaphos resistance in the major bee parasite Varroa destructor. PNAS. 118(6):e2020380118. DOI: 10.1073/pnas.2020380118. PMID: 33547243

(191) Sakka MK, Riga M, Ioannidis P, Baliota GV, Tselika M, Jagadeesan R, Nayak MK, Vontas J, Athanassiou CJ. (2021) Transcriptomic analysis of s-methoprene resistance in the lesser grain borer, Rhyzopertha dominica, and evaluation of piperonyl butoxide as a resistance breaker. BMC Genomics. 22(1):65. DOI:10.1186/s12864-020-07354-8. PMID: 33472593

(190) Nauen R, Zimmer C, Vontas J. (2021) Heterologous expression of insect P450 enzymes that metabolize xenobiotics. Curr Opin Insect Sci. 43:78-84. DOI: 10.1016/j.cois.2020.10.011. PMID: 33186746

(189) Vorgia E, Lamprousi M, Denecke S, Vogelsang K, Geibel S, Vontas J, Douris V. (2021) Functional characterization and transcriptomic profiling of a spheroid-forming midgut cell line from Helicoverpa zea (Lepidoptera: Noctuidae). Insect Biochem Mol Biol. 128:103510. DOI: 10.1016/j.ibmb.2020.103510. PMID: 33276037

(188) Swevers L, Denecke S, Vogelsang K, Geibel S, Vontas J. (2021) Can the mammalian organoid technology be applied to the insect gut? Pest Manag Sci. 77:55-63. DOI: 10.1002/ps.6067. PMID: 32865304

(187) Papapostolou KM, Riga M, Charamis J, Skoufa E, Souchlas V, Ilias A, Dermauw W, Ioannidis P, Van Leeuwen T, Vontas J. (2021) Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece. Pest Manag Sci. DOI: 10.1002/ps.6136. PMID: 33051974

(186) Xue W, Mermans C, Papapostolou KM, Lamprousi M, Christou IK, Inak E, Douris V, Vontas J, Dermauw W, Van Leeuwen T. (2021) Untangling a Gordian knot: the role of a GluCl3 I321T mutation in abamectin resistance in Tetranychus urticae. Pest Manag Sci. 77(4):1581-1593. DOI: 10.1002/ps.6215. PMID: 33283957


(185) Hin S, Baumgartner D, Specht M, Lüddecke J, Arjmand EM, Johannsen B, Schiedel L, Rombach M, Paust N, von Stetten F, Zengerle R, Wipf N, Müller P, Mavridis K, Vontas J, Mitsakakis K. (2020) VectorDisk: A microfluidic platform integrating diagnostic markers for evidence-based mosquito control. Processes. 8(12): 1-16. DOI: 10.3390/pr8121677

(184) Riga M, Ilias A, Vontas J, Douris V. (2020) Co-expression of a homologous cytochrome P450 reductase is required for in vivo validation of the Tetranychus urticae CYP392A16-based abamectin resistance in Drosophila. Insects. 11(12)::1-12. DOI: 10.3390/insects11120829. PMID: 33255521

(183) Vontas J, Katsavou E, Mavridis K. (2020) Cytochrome P450-based metabolic insecticide resistance in Anopheles and Aedes mosquito vectors: Muddying the waters. Pest Biochem Phys. 170:104666. DOI: 10.1016/j.pestbp.2020.104666. PMID: 32980073

(182) McLeman Α, Troczka BJ, Homem RA, Duarte A, Zimmer C, Garrood WT, Pym A, Beadle K, Reid RJ, Douris V, Vontas J, Davies TGE, Constant RE, Nauen R, Bass C. (2020) Fly-Tox: A panel of transgenic flies expressing pest and pollinator cytochrome P450s. Pestic Biochem Physiol. 169:104674. DOI: 10.1016/j.pestbp.2020.104674. PMID: 32828379

(181) Denecke SM, Driva O, Luong HNB, Ioannidis P, Linka M, Nauen R, Geibel S, Vontas J. (2020) The identification and evolutionary trends of the solute carrier superfamily in Arthropods. Genome Biol Evol. 12(8):1429-1439. DOI: 10.1093/gbe/evaa153. PMID: 32681801

(180) Balaska S, Fotakis EA, Kioulos I, Grigoraki L, Mpellou S, Chaskopoulou A, Vontas J. (2020) Bioassay and molecular monitoring of insecticide resistance status in Aedes albopictus populations from Greece, to support evidence-based vector control. Parasit Vectors. 13(1):328. DOI: 10.1186/s13071-020-04204-0. PMID: 32600453

(179) Douris V, Denecke S, Van Leeuwen T, Bass C, Nauen R, Vontas J. (2020) Using CRISPR/Cas9 genome modification to understand the genetic basis of insecticide resistance: Drosophila and beyond. Pest Biochem Phys. 167:104595. DOI: 10.1016/j.pestbp.2020.104595. PMID: 32527434

(178) Samantsidis GR, Panteleri R, Denecke S, Kounadi S, Christou I, Nauen R, Douris V, Vontas J. (2020) 'What I cannot create, I do not understand': Functionally validated synergism of metabolic and target site insecticide resistance. Proc Biol Sci. 287(1927):20200838. DOI: 10.1098/rspb.2020.0838. PMID:32453986

(177) Singh KS, Troczka BJ, Duarte A, Balabanidou V, Trissi N, Carabajal Paladino LZ, Nguyen P, Zimmer CT, Papapostolou KM, Randall E, Lueke B, Marec F, Mazzoni E, Williamson MS, Hayward A, Nauen R, Vontas J, Bass C. (2020) The genetic architecture of a host shift: An adaptive walk protected an aphid and its endosymbiont from plant chemical defenses. Sci. Adv. 6(19): eaba1070. DOI: 10.1126/sciadv.aba1070 PMID:32494720

(176) Van Leeuwen T, Dermauw W, Mavridis K, Vontas J. (2020) Significance and interpretation of molecular diagnostics for insecticide resistance management of agricultural pests. Curr Opin Insect Sci. 39:69-76. DOI: 10.1016/j.cois.2020.03.006. PMID:32361620

(175) Fotakis EA, Mastrantonio V, Grigoraki L, Porretta D, Puggioli A, Chaskopoulou A, Osório H, Weill M, Bellini R, Urbanelli S, Vontas J. (2020) Identification and detection of a novel point mutation in the Chitin Synthase gene of Culex pipiens associated with diflubenzuron resistance. PLoS Negl Trop Dis. 14(5):e0008284. DOI: 10.1371/journal.pntd.0008284. PMID:32357192

(174) Lueke B, Douris V, Hopkinson JE, Maiwald F, Hertlein G, Papapostolou KM, Bielza P, Tsagkarakou A, Van Leeuwen T, Bass C, Vontas J, Nauen R. (2020) Identification and functional characterization of a novel acetylCoA carboxylase mutation associated with ketoenol resistance in Bemisia tabaci. Pest Biochem Phys. 166:104583 DOI:10.1016/j.pestbp.2020.104583 PMID:32448413

(173) Fotakis EA, Giantsis IA, Castells Sierra J, Tanti F, Balaska S, Mavridis K, Kourtidis S, Vontas J, Chaskopoulou A. (2020) Population dynamics, pathogen detection and insecticide resistance of mosquito and sand fly in refugee camps, Greece. Infect Dis. Poverty. 9(1):30. DOI: 10.1186/s40249-020-0635-4. PMID:32183909

(172) Silva R, Mavridis K, Vontas J, Rodrigues A, Osorio H. (2020) Monitoring and molecular profiling of contemporary insecticide resistance status of malaria vectors in Guinea-Bissau. Acta Trop. 206:105440. DOI: 10.1016/j.actatropica.2020.105440. PMID:32156617

(171) Lynd A, Balabanidou V, Grosman R, Maas J, Lian LY, Vontas J, Lycett GJ (2020) Development of a functional genetic tool for Anopheles gambiae oenocyte characterisation: application to cuticular hydrocarbon synthesis. DOI:10.1101/742619 (in press)

(170) Koidou V, Denecke S, Ioannidis P, Vlatakis I, Livadaras I, Vontas J. (2020) Efficient genome editing in the olive fruit fly, Bactrocera oleae. Insect Mol Biol. 29(4):363-372. DOI: 10.1111/imb.12640. PMID: 32141659

(169) Wei P, Demaeght P, De Schutter K, Grigoraki L, Labropoulou V, Riga M, Vontas J, Nauen R, Dermauw W, Van Leeuwen T. (2020) Overexpression of an alternative allele of carboxyl/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto-enol acaricide pirodiclofen. Pest Manag Sci. 76(3):1142-1153. DOI: 10.1002/ps.5627. PMID: 31583806

(168) Traore MM, Junnila A, Traore SF, Doumbia S, Revay EE, Kravchenko VD, Schlein Y, Arheart KL, Gergely P, Xue RD, Hausmann A, Beck R, Prozorov A, Diarra RA, Kone AS, Majambere S, Bradley J, Vontas J, Beier JC, Müller GC. (2020) Large-scale field trial of attractive toxic sugar baits (ATSB) for the control of malaria vector mosquitoes in Mali, West Africa. Malar J. 19(1):72. DOI:10.1186/s12936-020-3132-0. PMID: 32059671

(167) Denecke S, Ioannidis P, Buer I, Ilias A, Douris V, Topalis P, Nauen R, Geibel S, Vontas J. (2020) A transcriptomic and proteomic atlas of expression in the Nezara viridula (Heteroptera: Pentatomidae) midgut suggests the compartmentalization of xenobiotic metabolism and nutrient digestion. BMC Genomics. 21(1):129. DOI: 10.1186/s12864-020-6459-6. PMID: 32028881

(166) Alavijeh ES, Khajehali J, Snoeck S, Panteleri R, Ghadamyari M, Jonckheere W, Bajda S, Saalwaechter C, Geibel S, Douris V, Vontas J, Van Leeuwen T, Dermauw W. (2020) Molecular and genetic analysis of resistance to METI-I acaricides in Iranian populations of the citrus red mite Panonychus citri. Pest Biochem Physiol. 164:73-84. DOI: 10.1016/j.pestbp.2019.12.009 PMID:32284140

(165) Blow F,  Gioti A, Goodhead IB, Kalyva M, Kampouraki A, Vontas J, Darby AC. (2020) Functional genomics of a symbiotic community: shared traits in the olive fruit fly gut microbiota. Genome Biol Evol. 12(2):3778-3791. DOI:10.1101/590489. PMID: 31830246

(164) Katsavou Ε, Vlogiannitis S, Karp-Tatham E, Blake DP, Ilias A, Strube C, Kioulos I, Dermauw W, Van Leeuwen T, Vontas J. (2020) Identification and geographical distribution of pyrethroid resistance mutations in the poultry red mite Dermanyssus gallinae. Pest Manag Sci. 76(1):125-133. DOI:10.1002/ps.5582. PMID:31400055

(163) Riga M, Denecke S, Livadaras I, Geibel S, Nauen R, Vontas J. (2020) Development of efficient RNAi in Nezara viridula for use in insecticide target discovery. Arch Insect Biochem Physiol. 103(3):e21650. DOI: 10.1002/arch.21650. PMID: 31833096

(162) Ingham VA, Anthousi A, Douris V, Harding NJ, Lycett G, Morris M, Vontas J, Ranson H. (2020) A sensory appendage protein protects malaria vectors from pyrethroids. Nature. 577(7790):376-380. DOI: 10.1038/s41586-019-1864-1. PMID: 31875852

(161) Dermauw W, Jonckheere W, Riga M, Livadaras I,  Vontas J, Van Leeuwen T. (2020) Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae. Insect Biochem Mol Biol. 120:103347 DOI:10.1016/j.ibmb.2020.103347. PMID: 32114158


(160) Guz N, Cagatay NS, Fotakis EA, Durmusoglu E, Vontas J. (2019) Detection of diflubenzuron and pyrethroid resistance mutations in Culex pipiens from Muğla, Turkey. Acta Trop. 10:105294. DOI: 10.1016/j.actatropica.2019.105294. PMID: 31836282

(159) Dusfour I, Vontas J, David JP, Weetman D, Fonseca DM, Corbel V, Raghavendra K, Coulibaly MB, Martins AJ, Kasai S, Chandre F. (2019) Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges. PLoS Negl Trop Dis. 13(10): e0007615. DOI:10.1371/journal.pntd.0007615. PMID:31600206

(158) Bamou R, Sonhafouo-Chiana N, Mavridis K, Tchuinkam T, Wondji CS, Vontas J, Antonio-Nkondjio C. (2019) Status of insecticide resistance and its mechanisms in Anopheles gambiae and Anopheles coluzzii populations from forest settings in South Cameroon. Genes. 10(10):741. DOI:10.3390/genes10100741. PMID:31554225

(157) Vontas J, Mavridis K. (2019) Vector population monitoring tools for insecticide resistance management: Myth or fact? Pest Biochem Physiol. 161:54-60. DOI:10.1016/j.pestbp.2019.08.005. PMID: 31685197

(156) Wybouw N, Kurlovs AH, Greenhalgh R, Bryon A, Kosterlitz O, Manabe Y, Osakabe M, Vontas J, Clark RM, Van Leeuwen T. (2019) Convergent evolution of cytochrome P450s underlies independent origins of keto-carotenoid pigmentation in animals. Proc R Soc B. 286(1907):20191039. DOI:10.1098/rspb.2019.1039. PMID: 31311468

(155) Balabanidou V, Kefi M, Aivaliotis M, Koidou V, Girotti JR, Mijailovsky SJ, Juárez MP, Papadogiorgaki E, Chalepakis G, Kampouraki A, Nikolaou C, Ranson H, Vontas J. (2019) Mosquitoes cloak their legs to resist insecticides. Proc R Soc B. 286(1907):20191091. DOI:10.1098/rspb.2019.1091. PMID: 31311476

(154) Corbel V, Durot C, Achee NL, Chandre F, Coulibaly MB, David JP, Devine GJ, Dusfour I, Fonseca DM, Griego J, Juntarajumnong W, Lenhart A, Kasai S, Martins AJ, Moyes Ng CC, Pinto J, Pompon JF, Muller P, Raghavendra K, Roiz D, Vatandoost H, Vontas J, Weetman D. (2019) Second WIN International Conference on “Integrated approaches and innovative tools for combating insecticide resistance in vectors of arboviruses”. Parasit Vector. 12:331. DOI:10.1186/s13071-019-3591-8. PMID: 31269996

(153) Tossou E, Tepa-Yotto G, Kpindou OKD, Sandeu R, Datinon B, Zeukeng F, Akoton R, Tchigossou GM, Djègbè I, Vontas J, Martin T, Wondji C, Tamò M, Bokonon-Ganta AH, Djouaka R. (2019) Susceptibility Profiles of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) to deltamethrin reveal a contrast between the northern and the southern Benin. Int J Environ Res Public Health. 16(11): E1882. DOI:10.3390/ijerph16111882 PMID: 31142024

(152) Kefi M, Balabanidou V, Douris V, Lycett G, Feyereisen R, Vontas J. (2019) Two functionally distinct CYP4G genes of Anopheles gambiae contribute to cuticular hydrocarbon biosynthesis. Insect Biochem Mol Biol. 110:52-59. DOI:10.1016/j.ibmb.2019.04.018 PMID: 31051237

(151) Tsakireli D, Riga M, Kounadi S, Douris V, Vontas J. (2019) Functional characterization of CYP6A51, a cytochrome P450 associated with pyrethroid resistance in the Mediterranean fruit fly Ceratitis capitata. Pest Biochem Physiol. 157:196-203. DOI:10.1016/j.pestbp.2019.03.022. PMID: 31153469

(150) Snoeck S, Pavlidi N, Pipini D, Vontas J, Dermauw W, Van Leeuwen T. (2019) Substrate specificity and promiscuity of horizontally transferred UDP-glucosyltransferases in the generalist herbivore Tetranychus urticae. Insect Biochem Mol Biol. 109:116-127. DOI:10.1016/j.ibmb.2019.04.010. PMID: 30978500

(149) Porretta D, Fotakis EA, Mastrantonio V, Chaskopoulou A, Michaelakis A, Kioulos I, Weill M, Urbanelli S, Vontas J, Bellini R. (2019) Focal distribution of diflubenzuron resistance mutations in Culex pipiens mosquitoes from Northern Italy. Acta Trop. 193:106-112. DOI: 10.1016/j.actatropica.2019.02.024. PMID: 30825446 

(148) Grant C, Jacobson R, Ilias A, Berger M, Bielza P, Zimmer CT, Williamson MS, French-Constant RH, Vontas J, Roditakis E, Bass C. (2019) The evolution of multiple-insecticide resistance in UK populations of tomato leafminer, Tuta absoluta. Pest Manag Sci. 75(8):2079-2085. DOI: 10.1002/ps.5381. PMID: 30785238

(147) Pichler V, Malandruccolo C, Paola S, Bellini R, Severini F, Toma L, Di Luca M, Montarsi F, Ballardini M, Manica M, Petrarca V, Vontas J, Kasai S, Della Torre A, Caputo B. (2019) Phenotypic and genotypic pyrethroid resistance of Aedes albopictus, with focus on the 2017 chikungunya outbreak in Italy. Pest Manag Sci. 75(10): 2642-2651. DOI: 10.1002/ps.5369. PMID: 30729706

(146) Guedes RNC, Roditakis E, Campos MR Haddi K, Bielza P, H. Siqueira HAA, Tsagkarakou A, Vontas J, Nauen R. (2019) Insecticide resistance in the tomato pinworm Tuta absoluta: patterns, spread, mechanisms, management and outlook. J Pest Sci. 92:1329-1342. DOI: 10.1007/s10340-019-01086-9

(145) Fotakis EA, Giantsis IA, Avgerinou A, Kourtidis S, Agathaggelidou E, Kapoula C, Dadakou G, Vontas J, Chaskopoulou A. (2019) Identification of Leishmania species in naturally infected sand flies from refugee camps, Greece. Emerg Infect Dis. 25(2):361-364. DOI: 10.3201/eid2502.181359. PMID: 30346269

(144) Mavridis Κ, Wipf Ν, Medves S, Erquiaga I, Müller P, Vontas J. (2019) Rapid multiplex gene expression assays for monitoring metabolic resistance in the major malaria vector Anopheles gambiae. Parasit Vector. 12(1):9 DOI:10.1186/s13071-018-3253-2. PMID:30612581

(143) Achee NL, Grieco JP, Vatandoost H, Seixas G, Pinto J, Ching-NG L, Martins AJ, Juntarajumnong W, Corbel V, Gouagna C, David JP, Logan JG, Orsborne J, Marois E, Devine GJ, Vontas J (2019) Alternative strategies for mosquito-borne arbovirus control. PLoS Negl Trop Dis.13(1): e0006822. DOI:10.1371/journal.pntd.0006822. PMID:30605475 (correction: DOI:10.1371/journal.pntd.0007275. PMID:30913223)

(142) Samantsidis G, O'Reilly AO, Douris V, Vontas J. (2019) Functional validation of target-site resistance mutations against sodium channel blocker insecticides (SCBIs) via molecular modeling and genome engineering in Drosophila. Insect Biochem Mol Biol. 104:73-081. DOI:10.1016/j.ibmb.2018.12.008. PMID:30572019

(141) Simma EA, Dermauw W, Balabanidou V, Snoeck S, Bryon A, Clark RM, Yewhalaw D, Vontas J, Duchateau L, Van Leeuwen T. (2019) Genome-wide gene expression profiling reveals that cuticle alterations and P450 detoxification are associated with pyrethroid resistance in Anopheles arabiensis populations from Ethiopia. Pest Manag. Sci. DOI: 10.1101/451336 PMID: 30740870 (in press)



(140) Walsh TK, Jouβen N, Tian KT, McGaughran A, Anderson CJ, Qiu X, Ahn SJ, Bird L, Pavlidi N, Vontas J, Ryu J, Rasool A, Barony Macedo I, Tay WT, Zhang YJ, Whitehouse M, Sylvie P, Downes S, Nemec L, Heckel DH. (2018). Multiple recombination events between two cytochrome P450 loci contribute to global pyrethroid resistance in Helicoverpa armigera. PLoSONE 13(11):e0197760. DOI: 10.1371/journal.pone.0197760  PMID:30383872

(139) Denecke S, Swevers L, Douris V,Vontas J. (2018). How do oral insecticidal compounds cross the insect midgut epithelium? Insect Biochem Mol Biol. 130:22-35. DOI: 10.1016/j.ibmb.2018.10.005. PMID: 30366055

(138) Bempelou ED, Vontas JG, Liapis KS, Ziogas NV. (2018). Biodegradation of chlorpyrifos and 3,5,6-trichloro-2-pyridinol by the epiphytic yeasts Rhodotorula glutinis and Rhodotorula rubra. Ecotoxicology. 27(10):1368-1378. DOI: 10.1007/s10646-018-1992-7 PMID:30343485

(137) Mavridis K, Wipf N, Müller P, Traorè MM, Muller G, Vontas J. (2018) Detection and Monitoring of Insecticide Resistance Mutations in Anopheles gambiae: Individual vs. Pooled Specimens. Genes. 9(10):E479. DOI:10.3390/genes9100479. PMID: 30282959

(136) Vontas J, Grigoraki L, Morgan J, Tsakireli D, Fuseini G, Segura L, Niemczura de Carvahlo J, Nguema R, Weetman D, Slotman MA, Hemingway J. (2018) Rapid selection of a pyrethroid metabolic enzyme CYP9K1 by operational malaria control activities. PNAS. 115(18):4619-4624. DOI:10.1073/pnas.1719663115. PMID: 29674455

(135) Fotakis EA, Giantsis IA, Demir S, Vontas JG, Chaskopoulou A. (2018) Detection of pyrethroid resistance mutations in the major leishmaniasis vector Phlebotomus papatasi. J Med. Entomol. 55(5): 1225-1230. DOI:10.1093/jme/tjy066. PMID: 29912381

(134) Çağatay NS, Riga M, Vontas J, Çevik B, Ay R. (2018) Biochemical and molecular characterizations of cypermethrin resistance in laboratory-selected cypermethrin-resistant strains of Tetranychus urticae Koch. (Acari: Tetranychidae). Int J Acarol. 44(6): 262-267. DOI: 10.1080/01647954.2018.1500641.

(133) Çağatay NS, Menault P, Riga M, Vontas J, Ay R. (2018) Identification and characterization of abamectin resistance in Tetranychus urticae Koch strains from greenhouses in Turkey. Crop Prot. 112:112-117. DOI:10.1016/j.cropro.2018.05.016.

(132) Kampouraki A, Stavrakaki M, Karataraki A, Katsikogiannis G, Pitika E, Varikou K, Vlachaki A, Chrysargyris A, Malandraki E, Sidiropoulos N, Paraskevopoulos A, Gilpathi D, Roditakis E, Vontas J. (2018) Recent evolution and operational impact of insecticide resistance in olive fruit fly Bactrocera oleae populations from Greece. J Pest Sci. 91(4):1429-1439. DOI:10.1007/s10340-018-1007-8.

(131) Pavlidi N, Kampouraki A, Tseliou V, Wybouw N, Dermauw W, Roditakis E, Nauen R, Van Leeuwen T, Vontas J. (2018) Molecular characterization of pyrethroid resistance in the olive fruit fly Bactrocera oleae. Pestic Biochem Phys. 148: 1-7 DOI:10.1016/j.pestbp.2018.03.011. PMID: 29891359

(130) Pavlidi N, Vontas J, VanLeeuwen T. (2018) The role of glutathione S-transferases (GSTs) in insecticide resistance in crop pests and disease vectors. Curr Opin Insect Sci. 27:97-102. DOI:10.1016/j.cois.2018.04.007 PMID:30025642

(129) Bajda S, Riga M, Wybouw N, Papadaki S, Ouranou E, Fotoukkiaii SM, Vontas J, Van Leeuwen T. (2018) Fitness costs of key point mutations that underlie acaricide target-site resistance in the two-spotted spider mite Tetranychus urticae. Evol Appl. 11(9): 1540-1553. DOI: PMID:30344626

(128) Balabanidou V, Grigoraki L, Vontas J. (2018) Insect cuticle: a critical determinant of insecticide resistance. Curr Opin Insect Sci. 27:68-74. DOI:10.1016/j.cois.2018.03.001 PMID:30025637

(127) Voudouris CC, Mavridis K, Kalaitzaki A, Skouras PJ, Kati AN, Eliopoulos PA, Vontas J, Margaritopoulos JT. (2018) Susceptibility of Ceratitis capitata to deltamethrin and spinosad in Greece. J Pest Sci. 91(2): 861-871. DOI:10.1007/s10340-017-0913-5

(126) Mavridis K, Fotakis EA, Kioulos I, Mpellou S, Konstantas S, Varela E, Gewehr S, Diamantopoulos V, Vontas J. (2018) Detection of West Nile Virus - Lineage 2 in Culex pipiens 1 mosquitoes, associated with disease outbreak in Greece. Acta Trop. 182:64-68. DOI:10.1016/j.actatropica.2018.02.024. PMID: 29474832

(125) Pichler V, Bellini R, Veronesi R, Arnoldi D, Rizzoli A, Lia RP, Otranto D, Montarsi F, Carlin S, Ballardini M, Antognini E, Salvemini M, Brianti E, Gaglio G, Manica M, Cobre P, Serini P, Velo E, Vontas J, Kioulos I, Pinto J, della Torre A, Caputo B. (2018) First evidence of resistance to pyrethroid insecticides in Italian Aedes albopictus populations 26 years after invasion. Pest Manag Sci. 74(6):1319-1327. DOI:10.1002/ps.4840. PMID: 29278457

(124) Pignatelli P, Ingham VA, Balabanidou V, Vontas J, Lycett G, Ranson H. (2018) The Anopheles gambiae ATP-binding cassette transporter family: phylogenetic analysis and tissue localization provide clues on function and role in insecticide resistance. Insect Mol Biol. 27(1):110–122. DOI:10.1111/imb.12351. PMID: 29068552

(123) Kefi M, Mavridis K, Simões ML, Dimopoulos G, Siden-Kiamos I, Vontas J. (2018) New rapid one-step PCR diagnostic assay for Plasmodium falciparum infective mosquitoes. Sci Rep. 8(1):1462. DOI:10.1038/s41598-018-19780-6. PMID: 29362379

(122) Kapantaidaki DE, Sadikoglou E, Tsakireli D, Kampanis V, Stavrakaki M, Schorn C, Ilias A, Riga M, Tsiamis G, Nauen R, Skavdis G, Vontas J, Tsagkarakou A. (2018) Insecticide resistance in Trialeurodes vaporariorum populations and novel diagnostics for kdr mutations. Pest Manag Sci. 74(1):59–69. DOI:10.1002/ps.4674. PMID: 28734106

(121) Mitsakakis K, Hin S, Müller P, Wipf N, Thomsen E, Coleman M, Zengerle R, Vontas J, Mavridis K. (2018) Converging human and malaria vector diagnostics with data management towards an integrated holistic One Health approach. Int J Environ Res Public Health. 15(2):259. DOI:10.3390/ijerph15020259. PMID: 29401670


(120) Yahouédo GA, Chandre F, Rossignol M, Ginibre C, Balabanidou V, Garcia Albeniz Mendez N, Pigeon O, Vontas J, Cornelie S. (2017) Contributions of cuticle permeability and enzyme detoxification to pyrethroid resistance in the major malaria vector Anopheles gambiae. Sci Rep 7:11091. DOI:10.1038/s41598-017-11357-z. PMID: 28894186  (correction: DOI:10.1038/s41598-018-24094-8. PMID: 29643452 )

(119) Alemayehu E, Asale A, Eba K, Getahun K, Tushune K, Bryon A, Morou E, Vontas J, Van Leeuwen T, Duchateau L, Yewhalaw D. (2017) Mapping insecticide resistance and characterization of resistance mechanisms in Anopheles arabiensis (Diptera: Culicidae) in Ethiopia. Parasit Vector. 10(1):407. DOI:10.1186/s13071-017-2342-y. PMID: 28865490 

(118) Grigoraki L, Puggioli A, Mavridis K, Douris V, Montanari M, Bellini R, Vontas J. (2017). Striking diflubenzuron resistance in Culex pipiens, the prime vector of West Nile Virus. Sci Rep. 7(1):11699. DOI:10.1038/s41598-017-12103-1. PMID: 28916816 (correction: DOI:10.1038/s41598-018-23059-1. PMID: 29650973)

(117) Corbel V, Fonseca DM, Weetman D, Pinto J, Achee NL, Chandre F, Coulibaly MB, Dusfour I, Grieco J, Juntarajumnong W, Lenhart A, Martins AJ, Moyes C, Lee Ching Ng, Raghavendra K, Vatandoost H, Vontas J, Muller P, Kasai S, Fouque F, Velayudhan R, Durot C, David JP. (2016) International workshop on insecticide resistance in vectors of arboviruses. Parasit Vectors. 10(1):278. DOI: 10.1186/s13071-017-2224-3. PMID: 28577363

(116) Seixas G, Grigoraki L, Weetman D, Vicente JL, Silva AC, Pinto J, Vontas J, Sousa CA. (2017) Insecticide resistance is mediated by multiple mechanisms in a recently introduced Aedes aegypti population from Madeira Island (Portugal). PLoS Negl Trop Dis 11(7):e0005799. DOI:10.1371/journal.pntd.0005799. PMID: 28742096

(115) Riga M, Bajda S, Themistokleous C, Papadaki S, Palzewicz M, Dermauw W, Vontas J, Van Leeuwen T. (2017) The relative contribution of target-site mutations in complex acaricide resistant phenotypes as assessed by marker assisted backcrossing in Tetranychus urticae. Sci Rep. 7(1):9202. DOI:10.1038/s41598-017-09054-y. PMID: 28835683

(114) Moyes C, Vontas J, Martins AJ, Ng LC, Koou SY, Dusfour I, Raghavendra K, Pinto J, Corbel V, David JP, Weetman D. (2017) Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans. PloS Negl Trop Dis. 11(7): e0005625. DOI:10.1371/journal.pntd.0005625. PMID: 28727779 (correction: DOI:10.1371/journal.pntd.0009084, PMID: 33465099)

(113) Douris V, Papapostolou KM, Ilias A, Roditakis E, Kounadi S, Riga M, Nauen R, Vontas J. (2017) Investigation of the contribution of RyR target-site mutations in diamide resistance by CRISPR/Cas9 genome modification in Drosophila. Insect Biochem Mol Biol. 87:127-135. DOI:10.1016/j.ibmb.2017.06.013. PMID: 28669775

(112) Santos-Matos G, Wybouw N, Martins NE, Zélé F, Riga M, Leitão AB, Vontas J, Grbić M, Van Leeuwen T, Magalhães S, Sucena É. (2017) Tetranychus urticae mites do not mount an induced immune response against bacteria. Proc Biol C. 284:20170401. DOI: 10.1098/rspb.2017.0401. PMID: 28592670

(111) Bryon A, Kurlovs AH, Dermauw W, Greenhalgh R, Riga M, Grbić M, Tirry L, Osakabe M, Vontas J, Clark RM, Van Leeuwen T.(2017) Disruption of a horizontally transferred phytoene desaturase abolishes carotenoid accumulation and diapause in Tetranychus urticae. PNAS. 114(29): E5871-5880. DOI:10.1073/pnas.1706865114. PMID: 28674017

(110) Fotakis EA, Chaskopoulou A, Grigoraki L, Tsiamantas A, Kounadi S, Georgiou L, Vontas J. (2017) Analysis of population structure and insecticide resistance in mosquitoes of the genus Culex, Anopheles and Aedes from different environments of Greece with a history of mosquito borne disease transmission. Acta Trop. 174:29-37. DOI: 0.1016/j.actatropica.2017.06.005. PMID: 28606820

(109) Grigoraki L, Pipini D, Labbé P, Chaskopoulou A, Weill M, Vontas J. (2017) Carboxylesterase gene amplifications associated with insecticide resistance in Aedes albopictus: Geographical distribution and evolutionary origin. PLOS Negl Trop Dis. 11(4):e0005533. DOI:10.1371/journal.pntd.0005533. PMID: 28394886

(108) Blow F, Vontas J, Darby AC. (2017) Draft Genome Sequence of Chryseobacterium Strain CBo1 Isolated from Bactrocera oleae. Genome Announc. 5(18):e00177-17. DOI: 10.1128/genomeA.00177-17. PMID: 28473371

(107) Roditakis E, Mavridis K, Riga M, Vasakis E, Morou E, Rison J, Vontas J. (2017) Identification and detection of indoxacarb resistance mutations in the para sodium channel of the tomato leafminer, Tuta absoluta. Pest Manag Sci. 73(8):1679-1688. DOI: 10.1002/ps.4513. PMID: 28019074

(106) Pavlidi N, Mousaalreza K, Myridakis A, Dermauw W, Wybouw N, Tsakireli D, Stephanou EG, Labrou NE, Vontas J, Van Leeuwen T. (2017) A glutathione-S-transferase (TuGSTd05) associated with acaricide resistance in Tetranychus urticae directly metabolizes the complex II inhibitor cyflumetofen. Insect Biochem Mol Biol. 80:101-115, DOI: 10.1016/j.ibmb.2016.12.003. PMID: 27932274

(105) Roditakis E, Steinbach D, Moritz G, Vasakis E, Stavrakaki M, Ilias A, Vidal LG, Martínez-Aguirre MDR, Bielza P, Morou E, Silva JE, Silva WM, Siqueira Η, Iqbal S, Troczka BJ, Williamson M, Bass C, Tsagkarakou A, Vontas J, Nauen R. (2017) Ryanodine receptor point mutations confer diamide insecticide resistance in tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae). Insect Biochem Mol Biol. 80:11-20 DOI: 10.1016/j.ibmb.2016.11.003. PMID: 27845250

(104) Bajda S, Dermauw W, Panteleri R, Sugimoto N, Douris V, Tirry L, Osakabe M, Vontas J, Van Leeuwen T. (2017) A mutation in the PSST homologue of complex I (NADH:ubiquinone oxidoreductase) from Tetranychus urticae is associated with resistance to METI acaricides. Insect Biochem Mol Biol. 80:79-90. DOI:10.1016/j.ibmb.2016.11.010. PMID: 27919778

(103) Pavlidi N, Gioti A, Wybouw N, Dermauw W, Ben-Yosef M, Yuval B, Jurkevich E, Kampouraki A, Van Leeuwen T, Vontas J. (2017) Transcriptomic responses of the olive fruit fly Bactrocera oleae and its symbiont Candidatus Erwinia dacicola to olive feeding. Sci Rep. 7:42633 DOI: 10.1038/srep42633. PMID: 28225009

(102) Longdon B,  Day JP, Schulz N, Leftwich PT,  de Jong MA, Breuker CJ, Gibbs M, Obbard DJ, Wilfert L, Smith SCL, McGonigle JE, Houslay TM, Wright LI, Livraghi L,  Evans LC, Friend LA, Chapman T, Vontas J, Kambouraki N, Jiggins FM. (2017) Vertically transmitted rhabdoviruses are found across three insect families and have dynamic interactions with their hosts. Proc Biol C. 284:20162381. DOI:10.1098/rspb.2016.2381. PMID: 28100819

(101) Ilias A, Vassiliou V, Vontas J, Tsagkarakou A. (2017) Molecular diagnostics for detecting pyrethroid and abamectin resistance mutations in Tetranychus urticae. Pestic Biochem Phys. 135:9-14. DOI:10.1016/j.pestbp.2016.07.004. PMID: 28043338


(100) Douris V, Steinbach D, Panteleri R, Livadaras I, Pickett JA, Van Leeuwen T, Nauen R, Vontas J. (2016) Resistance mutation conserved between insects and mites unravels the benzoylurea insecticide mode of action on chitin biosynthesis. PNAS. 113(51):14692–14697. DOI:10.1073/pnas.1618258113. PMID: 27930336

(99) Corbel V, Achee ΝL, Chandre F, Coulibaly MB, Dusfour I, Fonseca DM, Grieco J, Juntarajumnong W, Lenhart A, Martins AJ, Moyes C, Ng LC, Pinto J, Raghavendra K, Vatandoost H, Vontas J, Weetman D, Fouque F, Velayudhan R, David JP. (2016) Tracking Insecticide resistance in mosquito vectors of Arboviruses: The Worldwide Insecticide resistance Network (WIN). PLOS Negl Trop Dis. 10(12):e0005054. DOI:10.1371/journal.pntd.0005054. PMID: 27906961

(98) Vontas J, Mitsakakis K, Zengerle R, Yewhalaw D, Sikaala CH, Etang J, Fallani M, Carman B, Müller P, Chouaïbou M, Coleman M, Coleman M. (2016). Automated innovative diagnostic, data management and communication tool, for improving malaria vector control in endemic settings. Stud Health Technol Inform. 224:54-60. DOI: 10.3233/978-1-61499-653-8-54. PMID: 27225553

(97) Stilianakis NI, Syrris V, Petroliagkis T, Pärt P, Gewehr S, Kalaitzopoulou S, Mourelatos S, Baka A, Pervanidou D, Vontas J, Hadjichristodoulou C. (2016) Identification of climatic factors affecting the epidemiology of human west nile virus infections in northern Greece. PLoS One. 11(9):e0161510. DOI:10.1371/journal.pone.0161510. PMID: 27631082

(96) Grigoraki L, Balabanidou V, Pipini D, Strati F, Vontas J. (2016) Analysis of Insecticide Resistance in Mosquito Disease Vectors: From Molecular Mechanisms to Management - Arthropod-borne Infectious Diseases and Arthropods as Disease Agents. Nova Act Lc. 411:165-171

(95) Balabanidou V, Kampouraki A, MacLean M, Blomquist GJ, Tittiger C, Juarez MP, Mijailovsky SJ, Chalepakis G, Anthousi A, Lynd A, Antoine S, Hemingway J, Ranson H, Lycett GJ, Vontas J. (2016) Cytochrome P450 associated with insecticide resistance catalyzes cuticular hydrocarbon production in Anopheles gambiae. PNAS. 113(33):9268-9273. DOI: 10.1073/pnas.1608295113 PMID: 27439866.

(94) Grigoraki L, Balabanidou V, Meristoudis C, Miridakis A, Ranson H, Swevers L, Vontas J. (2016) Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus. Insect Biochem Mol Biol. 74:61-67. DOI:10.1016/j.ibmb.2016.05.007. PMID: 27180726

(93) Blow F, Gioti A, Starns D, Ben-Yosef M, Pasternak Z, Jurkevitch E, Vontas J, Darby AC. (2016) Draft genome sequence of the Bactrocera oleae symbiont “Candidatus Erwinia dacicola”. Genome Announc. 4(5):e00896-16. DOI:10.1128/genomeA.00896-16Genome. PMID: 27634990

(92) Blow F, Vontas J, Darby AC. (2016) Draft Genome Sequence of Stenotrophomonas maltophilia SBo1 isolated from Bactrocera oleae. Genome Announc. DOI:10.1128/genomeA.00905-16 Genome. 4(5):e00905-16. PMID: 27660769


(91) Chen X, Jiang X, Gu J, Xu M, Wu Y, Deng Y, Zhang C, Bonizzoni M, Dermauw W, Vontas J, Armbruster P, Huang X, Yang Y, Hao Z, He W, Peng H, Liu Y, Wu K, Chen J, Lirakis M, Topalis P, Van Leeuwen T, Hall AB, Jiang X, Thorpe C, Mueller RL, Sun C, Waterhouse RM, Yan G, Tu ZJ, Fang X, James AA. (2015) Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics and evolution. PNAS. 112(44):E5907-E5915. DOI:10.1073/pnas.1516410112. PMID: 26483478

(90) Riga M, Myridakis A, Tsakireli D, Morou E, Stephanou EG, Nauen R, Van Leeuwen T, Douris V, Vontas J. (2015) Functional characterization of the Tetranychus urticae CYP392A11, a cytochrome P450 that hydroxylates the METI acaricides cyenopyrafen and fenpyroximate. Insect Biochem Mol Biol. 65:91-99. DOI:10.1016/j.ibmb.2015.09.004. PMID: 26363294

(89) Jones CM, Papanicolaou A, Mironidis GK, Vontas J, Yang Y, Lim KS, Oakeshott JG, Bass C, Chapman JW. (2015) Genomewide transcriptional signatures of migratory flight activity in a globally invasive insect pest. Mol Ecol. 24(19):4901-4911. DOI:10.1111/mec.13362. PMID: 26331997

(88) Ilias A, Lagnel J, Kapantaidaki D, Roditakis E, Tsigenopoulos C, Vontas J, Tsagkarakou A. (2015) Transcription analysis of neonicotinoid resistance in Mediterranean (MED) populations of B. tabaci reveal novel cytochrome P450s, but no nAChR mutations associated with the phenotype. BMC Genomics. 16:939. DOI: 10.1186/s12864-015-2161-5. PMID: 26573457

(87) Halon E, Eakteiman G, Moshitzky P, Elbaz M, Alon M, Pavlidi N, Vontas J, Morin S. (2015) Only a minority of broad-range detoxification genes respond to a variety of phytotoxins in generalist Bemisia tabaci species. Sci Rep. 10(5):17975. DOI:10.1038/srep17975. PMID: 26655836

(86) Grigoraki L, Lagnel J, Kioulos I, Kampouraki A, Morou E, Labbé P, Weill M, Vontas J. (2015) Transcriptome Profiling and Genetic Study Reveal Amplified Carboxylesterase Genes Implicated in Temephos Resistance, in the Asian Tiger Mosquito Aedes albopictus. PLoS Negl Trop Dis. 9(5):e0003771. DOI:10.1371/journal.pntd.0003771. PMID: 26000638

(85) AlSuhaibani E, Voudouris CC, Al-Atiyat R, Kotzamumin A, Vontas J, Margaritopoulos JT. (2015) Identification of a point mutation in the ace1 gene of Therioaphis trifolli maculata and detection of insecticide resistance by a diagnostic PCR-RFLP assay. Bull Entomol Res. 105(6):712-716. DOI:10.1017/S0007485315000668. PMID: 26278202

(84) Nauen R, Wölfel K, Lueke B, Myridakis A, Tsakireli D, Roditakis E, Tsagkarakou A, Stephanou E, Vontas J. (2015). Development of a lateral flow test to detect metabolic resistance in Bemisia tabaci mediated by CYP6CM1, a cytochrome P450 with broad spectrum catalytic efficiency. Pestic Biochem Physiol. 121:3-11. DOI: 10.1016/j.pestbp.2014.12.023. PMID: 26047106

(83) Pavlidi N, Tseliou V, Riga M, Nauen R, Van Leeuwen T, Labrou NE, Vontas J. (2015). Functional characterization of glutathione S-transferases associated with insecticide resistance in Tetranychus urticae. Pestic Biochem Physiol. 121:53-60. DOI:10.1016/j.pestbp.2015.01.009. PMID: 26047112

(82) Thawer NG, Ngondi JM, Mugalura FE, Emmanuel I, Mwalimu CD, Morou E, Vontas J, Protopopoff N, Rowland M, Mutagahywa J, Lalji S, Molteni F, Ramsan MM, Willilo R, Wright A, Kafuko JM, Ndong I, Reithinger R, Magesa SM. (2015) Use of Insecticide Quantification Kits to investigate the quality of spraying and decay rate of Bendiocarb on different wall surfaces in Kagera region, Tanzania. Parasit Vector. 8:242. DOI:10.1186/s13071-015-0859-5. PMID: 25896604

(81) Neafsey DE, Waterhouse RM, Abai MR, ...Vontas J,..., Zwiebel L, Besansky N. (2015) Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes. Sci. 347(6217):1258522 DOI: 10.1126/science.1258522. PMID: 25554792


(80) Leftwich PT, Koukidou M, Rempoulakis P, Gong HF, Zacharopoulou A, Fu G, Chapman T, Economopoulos A, Vontas J, Alphey L. (2014) Genetic elimination of field-cage populations of Mediterranean fruit flies. Proc Biol C. 281:20141372. DOI:10.1098/rspb.2014.1372. PMID: 25122230

(79) Ingham VA, Jones CM, Pignatelli P, Balabanidou V, Vontas J, Wagstaff SC, Moore JD, Ranson H. (2014) Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae: known and novel candidate genes. BMC Genomics. 15:1018. DOI: 10.1186/1471-2164-15-1018. PMID: 25421852

(78) Ilias A, Vontas J, Tsagkarakou A. (2014) Global distribution and origin of target site insecticide resistance mutations in Tetranychus urticae. Insect Biochem Mol Biol. 48:17-28. DOI:10.1016/j.ibmb.2014.02.006. PMID: 24602758

(77) Kioulos I, Kampouraki A, Morou E, Skavdis G, Vontas J. (2014) Insecticide resistance status in the major West Nile virus vector Culex pipiens from Greece. Pest Manag Sci. 70(4):623-627. DOI:10.1002/ps.3595. PMID: 23788440

(76) Riga M, Tsakireli D, Ilias A, Morou E, Myridakis A, Stephanou EG, Nauen R, Dermauw W, Van Leeuwen T, Paine M, Vontas J. (2014) Abamectin is metabolized by CYP392A16, a cytochrome P450 associated with high levels of acaricide resistance in Tetranychus urticae. Insect Biochem Mol Biol. 46:43-53. DOI:10.1016/j.ibmb.2014.01.006. PMID: 24463358

(75) Roditakis E, Fytrou N, Staurakaki M, Vontas J, Tsagkarakou A. (2014) Activity of flonicamid on the sweet potato whitely Bemisia tabaci (Homoptera: Aleyrodidae) and its natural enemies. Pest Manag Sci. 70(10):1460-1467. DOI:10.1002/ps.3723. PMID: 24408346

(74) Vontas J, Moore S, Kleinschmidt I, Ranson H, Lindsay S, Lengeler C, Hamon N, McLean T, Hemingway J. (2014) Framework for rapid assessment and adoption of new vector control tools. Trends Parasitol. 30(4):191-204. DOI:10.1016/ PMID: 24657042


(73) Bempelou ED, Vontas J, Liapis KS, Ziogas VN. (2013) Biodegradation of diazinon by the epiphytic yeasts Rhodotorula glutinis and Rhodotorula rubra. Hellenic Plant Prot J. 6(2):69-82. ISSN:1791-3691

(72) Hemingway J, Vontas J, Poupardin R, Raman J, Lines J, Schwabe C, Matias A, Kleinschmidt I. (2013) Country-level operational implementation of the Global Plan for Insecticide Resistance Management. PNAS. 110(23):9397-9402. DOI:10.1073/pnas.1307656110. PMID: 23696658

(71) Dermauw W, Wybouw N, Rombauts S, Menten B, Vontas J, Grbic M, Clark RM, Feyereisen R, Van Leeuwen T. (2013) A link between host plant adaptation and pesticide resistance in the polyphagous spider mite Tetranychus urticae. PNAS. 110(2):E113-E122. DOI:10.1073/pnas.1213214110. PMID: 23248300

(70) Demaeght P, Dermauw W, Tsakireli D, Khajehali J, Nauen R, Tirry L, Vontas J, Lümmen P, Van Leeuwen T. (2013) Molecular analysis of resistance to acaricidal spirocyclic tetronic acids in Tetranychus urticae: CYP392E10 metabolizes spirodiclofen, but not its corresponding enol. Insect Biochem Mol Biol. 43(6):544-554. DOI:10.1016/j.ibmb.2013.03.007. PMID: 23523619

(69) Gomes B, Kioulos Ε, Papa A, Almeida APG, Vontas J, Pinto J. (2013) Distribution and hybridization of Culex pipiens forms in Greece during the West Nile virus outbreak of 2010. Infect Genet Evol. 16:218-225. DOI:10.1016/j.meegid.2013.02.006. PMID: 23466890

(68) Mironidis GK, Kapantaidaki D, Bentila M, Morou E, Savopoulou-Soultani M, Vontas J. (2013) Resurgence of the cotton bollworm Helicoverpa armigera in northern Greece associated with insecticide resistance. Insect Sci. 20(4):505-512. DOI:10.1111/j.1744-7917.2012.01528.x. PMID: 23955946

(67) Morou E, Lirakis M, Pavlidi N, Zotti M, Nakagawa Y, Smagghe G, Vontas J, Swevers L. (2013) A new dibenzoylhydrazine with insecticidal activity against Anopheles mosquito larvae. Pest Manag Sci. 69(7):827-833. DOI:10.1002/ps.3441. PMID: 23208761


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