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    Publications Housed or mice generated, selected publications ES cell technology, DNA microinjection

    Housed mice


    Grasso F, Mochi S, Fratini F, Olivieri A, Currà C, Siden-Kiamos I, Deligianni E, Birago C, Picci L, Pizzi E, Pace T, Ponzi M. (2020) A comprehensive gender-related secretome of Plasmodium berghe i sexual stages. Mol Cell Proteomics. mcp.RA120.002212. doi: 10.1074/mcp.RA120.002212. Online ahead of print.

    Kalafatakis I, Kalafatakis K, Tsimpolis A, Giannakeas N, Tsipouras M, Tzallas A, Karagogeos D. (2020) Using the Allen Gene Expression Atlas of the Adult Mouse Brain to Gain Further Insight Into the Physiological Significance of TAG-1/Contactin-2. Brain Struct Funct. 225:2045-2056.

    Kokras N, Dioli C, Paravatou R, Sotiropoulos MG, Delis F, Antoniou K, Calogeropoulou T, Charalampopoulos I, Gravanis A, Dalla C. (2020) Psychoactive Properties of BNN27, a Novel Neurosteroid Derivate, in Male and Female Rats. Psychopharmacology (Berl). 237:2435-2449.

    Chatzidoukaki O, Goulielmaki E, Schumacher B, Garinis GA. (2020) DNA Damage Response and Metabolic Reprogramming in Health and Disease. Trends Genet. S0168-9525(20)30166-9. Online ahead of print.

    Nasias D, Dalakoura-Karagkouni K, Vassou D, Papagiannakis G, Papadaki A, Kardassis D. (2020) Transcriptome analysis of the adipose tissue in a mouse model of metabolic syndrome identifies gene signatures related to disease pathogenesis. Genomics. S0888-754331032-8.

    Thymiakou E, Othman A, Hornemann T, Kardassis D. (2020) Defects in high density lipoprotein metabolism and hepatic steatosis in mice with liver-specific ablation of hepatocyte nuclear factor 4α. Metabolism. 154307.

    Andreadaki M, Pace T, Grasso F, Siden-Kiamos I, Mochi S, Picci L, Bertuccini L, Ponzi M, Currà C. (2020) Plasmodium berghei Gamete Egress Protein is required for fertility of both genders. Microbiologyopen. 9:e1038.

    Biosca A, Bouzón-Arnáiz I, Spanos L, Siden-Kiamos I, Iglesias V, Ventura S, Fernàndez-Busquets X. (2020) Detection of Protein Aggregation in Live Plasmodium Parasites. Antimicrob Agents Chemother. 64:e02135-19

    Siden-Kiamos I, Spanos L, Currà C. (2020) A method for purification of Plasmodium oocysts from mosquito midguts. Sci Rep. 10:7262.

    Karagianni P, Moulos P, Schmidt D, Odom DT, Talianidis I. (2020) Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation. Cell Rep. 30:1319-1328.e6.

    Delivanoglou N, Boziki M, Theotokis P, Kesidou E, Touloumi O, Dafi N, Nousiopoulou E, Lagoudaki R, Grigoriadis N, Charalampopoulos I, Simeonidou C. (2020) Spatio-temporal expression profile of NGF and the two-receptor system, TrkA and p75NTR, in experimental autoimmune encephalomyelitis. J Neuroinflammation. 17:41.

    Gutiérrez L, Caballero N, Fernández-Calleja L, Karkoulia E, Strouboulis J. (2020) Regulation of GATA1 levels in erythropoiesis. IUBMB Life. 72:89-105.

    Siden-Kiamos I, Goosmann C, Buscaglia CA, Brinkmann V, Matuschewski K, Montagna GN. (2020) Polarization of MTIP is a signature of gliding locomotion in Plasmodium ookinetes and sporozoites. Mol Biochem Parasitol. 235:111247.

    Goulielmaki E, Ioannidou A, Tsekrekou M, Stratigi K, Poutakidou IK, Gkirtzimanaki K, Aivaliotis M, Evangelou K, Topalis P, Altmüller J, Gorgoulis VG, Chatzinikolaou G, Garinis GA. (2020) Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage. Nat Commun. 11:42.


    Apostolou Z, Chatzinikolaou G, Stratigi K, Garinis GA. (2019) Nucleotide Excision Repair and Transcription-Associated Genome Instability. Bioessays. 41(4):e1800201.

    Bastakis GG, Ktena N, Karagogeos D, Savvaki M. (2019) Models and Treatments for Traumatic Optic Neuropathy and Demyelinating Optic Neuritis. Dev Neurobiol. 79:819-836.

    Chroni A, Kardassis D. (2019) HDL dysfunction caused by mutations in apoA-I and other genes that are critical for HDL biogenesis and remodeling. Curr Med Chem. 26:1544-1575.

    Currà C, Kehrer J, Lemgruber L, Silva PAGC, Bertuccini L, Superti F, Pace T, Ponzi M, Frischknecht F, Siden-Kiamos I, Mair GR. (2019) Malaria transmission through the mosquito requires the function of the OMD protein. PLoS One. 14:e0222226.

    Kalafatakis K, Giannakeas N, Lightman SL, Charalampopoulos I, Russell GM, Tsipouras M, Tzallas A. (2019) Utilization of the Allen Gene Expression Atlas to gain further insight into glucocorticoid physiology in the adult mouse brain. Neurosci Lett. 706:194-200.

    Kastriti ME, Stratigi A, Mariatos D, Theodosiou M, Savvaki M, Kavkova M, Theodorakis K, Vidaki M, Zikmund T, Kaiser J, Adameyko I, Karagogeos D. (2019) Ablation of CNTN2+ Pyramidal Neurons During Development Results in Defects in Neocortical Size and Axonal Tract Formation. Front Cell Neurosci. 13:454.

    Nasias D, Evangelakos I, Nidris V, Vassou D, Tarasco E, Lutz TA, Kardassis D. (2019) Significant changes in hepatic transcriptome and circulating miRNAs are associated with diet-induced metabolic syndrome in apoE3L.CETP mice. J Cell Physiol. 234:20485-20500.

    Papandreou ME, Tavernarakis N. (2019) Nucleophagy: from homeostasis to disease. Cell Death Differ. 26:630-639.

    Patsalos A, Tzerpos P, Halasz L, Nagy G, Pap A, Giannakis N, Lyroni K, Koliaraki V, Pintye E, Dezso B, Kollias G, Spilianakis CG, Nagy L. (2019) The BACH1-HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration. J Immunol. 203:1532-1547.

    Salataj E, Stathopoulou C, Hafþórsson RA, Nikolaou C, Spilianakis CG. (2019) Developmental conservation of microRNA gene localization at the nuclear periphery. PLoS One. 14:e0223759.

    Tarasco E, Boyle CN, Pellegrini G, Arnold M, Steiner R, Hornemann T, Nasias D, Kardassis D, Whiting L, Lutz TA. (2019) Body weight-dependent and independent improvement in lipid metabolism after Roux-en-Y gastric bypass in ApoE*3Leiden.CETP mice. Int J Obes (Lond). 43(12):2394-2406.

    Vatikioti A, Karkoulia E, Ioannou M, Strouboulis J. (2019) Translational regulation and deregulation in erythropoiesis. Exp Hematol. 75:11-20.

    Vogiatzi A, Mavrothalassitis G. (2019) Craniofacial, orofacial and dental disorders: the role of the RAS/ERK pathway. Expert Rev Mol Med. 21:e2.


    Andrianaki AM, Kyrmizi I, Thanopoulou K, Baldin C, Drakos E, Soliman SSM, Shetty AC, McCracken C, Akoumianaki T, Stylianou K, Ioannou P, Pontikoglou C, Papadaki HA, Tzardi M, Belle V, Ettiene E, Beauvais A, Samonis G, Kontoyiannis DP, Andreakos E, Bruno VM, Ibrahim AS, Chamilos G. (2018) Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species. Nat Commun. 2018 Aug 20;9(1):3333.

    Deligianni E, Silmon de Monerri NC, McMillan PJ, Bertuccini L, Superti F, Manola M, Spanos L, Louis C, Blackman MJ, Tilley L, Siden-Kiamos I. (2018) Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage. PLoS One. 2018 Aug 13;13(8):e0201651.

    Alexaki VI, Fodelianaki G, Neuwirth A, Mund C, Kourgiantaki A, Ieronimaki E, Lyroni K, Troullinaki M, Fujii C, Kanczkowski W, Ziogas A, Peitzsch M, Grossklaus S, Sönnichsen B, Gravanis A, Bornstein SR, Charalampopoulos I, Tsatsanis C, Chavakis T. (2018) DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway. Mol Psychiatry. 2018 Jun;23(6):1410-1420.

    Chroni A, Kardassis D. (2018) HDL dysfunction caused by mutations in apoA-I and other genes that are critical for HDL biogenesis and remodeling. Curr Med Chem. 2018 Mar 12. [Epub ahead of print]

    Konstantoudaki X, Chalkiadaki K, Vasileiou E, Kalemaki K, Karagogeos D, Sidiropoulou K. (2018) Prefrontal cortical-specific differences in behavior and synaptic plasticity between adolescent and adult mice. J Neurophysiol. 2018 Mar 1;119(3):822-833.

    Zoupi L, Savvaki M, Kalemaki K, Kalafatakis I, Sidiropoulou K, Karagogeos D. (2018) The function of contactin-2/TAG-1 in oligodendrocytes in health and demyelinating pathology. Glia. 2018 Mar;66(3):576-591.


    Stathopoulou C, Kapsetaki M, Stratigi K, Spilianakis C. (2017) Long non-coding RNA SeT and miR-155 regulate the Tnfα gene allelic expression profile. PLoS One. 2017 Sep 14;12(9):e0184788.

    Peraki I, Palis J, Mavrothalassitis G. (2017) The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis. Mol Cell Biol. 2017 Sep 12;37(19). pii: e00183-17.

    Kanaki M, Tiniakou I, Thymiakou E, Kardassis D. (2017) Physical and functional interactions between nuclear receptor LXRα and the forkhead box transcription factor FOXA2 regulate the response of the human lipoprotein lipase gene to oxysterols in hepatic cells. Biochim Biophys Acta. 2017 Aug;1860(8):848-860.

    Bonetto G, Charalampopoulos I, Gravanis A, Karagogeos D. (2017) The novel synthetic microneurotrophin BNN27 protects mature oligodendrocytes against cuprizone-induced death, through the NGF receptor TrkA. Glia. 2017 Aug;65(8):1376-1394.

    Nikolaou KC, Moulos P, Harokopos V, Chalepakis G, Talianidis I. (2017) Kmt5a Controls Hepatic Metabolic Pathways by Facilitating RNA Pol II Release from Promoter-Proximal Regions. Cell Rep. 2017 Jul 25;20(4):909-922.

    Hadjimichael C, Chanoumidou K, Nikolaou C, Klonizakis A, Theodosi GI, Makatounakis T, Papamatheakis J, Kretsovali A. (2017) Promyelocytic Leukemia Protein Is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming. Stem Cell Reports. 2017 May 9;8(5):1366-1378.

    Botsakis K, Mourtzi T, Panagiotakopoulou V, Vreka M, Stathopoulos GT, Pediaditakis I, Charalampopoulos I, Gravanis A, Delis F, Antoniou K, Zisimopoulos D, Georgiou CD, Panagopoulos NT, Matsokis N, Angelatou F. (2017) BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the "weaver" mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor. Neuropharmacology. 2017 Apr 28;121:140-157.

    Vorgia E, Zaragkoulias A, Peraki I, Mavrothalassitis G. (2017) Suppression of Fgf2 by ETS2 repressor factor (ERF) is required for chorionic trophoblast differentiation. Mol Reprod Dev. 2017 Apr;84(4):286-295.

    Trusca VG, Fuior EV, Fenyo IM, Kardassis D, Simionescu M, Gafencu AV. (2017) Differential action of glucocorticoids on apolipoprotein E gene expression in macrophages and hepatocytes. PLoS One. 2017 Mar 29;12(3):e0174078.

    Kanaki M, Kardassis D. (2017) Regulation of the human lipoprotein lipase gene by the forkhead box transcription factor FOXA2/HNF-3β in hepatic cells. Biochim Biophys Acta. 2017 Mar;1860(3):327-336.

    Gravanis A, Pediaditakis I, Charalampopoulos I. (2017) Synthetic microneurotrophins in therapeutics of neurodegeneration. Oncotarget. 2017 Feb 7;8(6):9005-9006.

    Koussis K, Goulielmaki E, Chalari A, Withers-Martinez C, Siden-Kiamos I, Matuschewski K, Loukeris TG. (2017) Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host. PLoS One. 12(1):e0170260


    Currà C, Gessmann R, Pace T, Picci L, Peruzzi G, Varamogianni-Mamatsi V, Spanos L, Garcia CR, Spaccapelo R, Ponzi M, Siden-Kiamos I. (2016) Release of Plasmodium sporozoites requires proteins with histone-fold dimerization domains. Nat Commun. 7:13846

    Favicchio R, Psycharakis S, Schönig K, Bartsch D, Mamalaki C, Papamatheakis J, Ripoll J, Zacharakis G. (2016) Quantitative performance characterization of three-dimensional noncontact fluorescence molecular tomography. J Biomed Opt. 2016 Feb;21(2):26009.

    Gkouskou KK, Ioannou M, Pavlopoulos GA, Georgila K, Siganou A, Nikolaidis G, Kanellis DC, Moore S, Papadakis KA, Kardassis D, Iliopoulos I, McDyer FA, Drakos E, Eliopoulos AG. (2016) Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis. Oncogene. 35(19):2496-505.

    Glajch KE, Ferraiuolo L, Mueller KA, Stopford MJ, Prabhkar V, Gravanis A, Shaw PJ, Sadri-Vakili G. (2016) MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis. PLoS One. 2016 Oct 7;11(10):e0164103.

    Pediaditakis I, Efstathopoulos P, Prousis KC, Zervou M, Arévalo JC, Alexaki VI, Nikoletopoulou V, Karagianni E, Potamitis C, Tavernarakis N, Chavakis T, Margioris AN, Venihaki M, Calogeropoulou T, Charalampopoulos I, Gravanis A (2016) Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation. Neuropharmacology.111:266-282

    Oliverio M, Schmidt E, Mauer J, Baitzel C, Hansmeier N, Khani S, Konieczka S, Pradas-Juni M, Brodesser S, Van TM, Bartsch D, Brönneke HS, Heine M, Hilpert H, Tarcitano E, Garinis GA, Frommolt P, Heeren J, Mori MA, Brüning JC, Kornfeld JW. (2016) Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function. Nat Cell Biol. 18(3):328-36

    Vyrla D, Nikolaidis G, Oakley F, Perugorria MJ, Tsichlis PN, Mann DA, Eliopoulos AG. (2016) TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury. J Immunol. 2016 May 15;196(10):4298-310.

    Konstantoudaki X, Chalkiadaki K, Tivodar S, Karagogeos D, Sidiropoulou K. (2016) Impaired synaptic plasticity in the prefrontal cortex of mice with developmentally decreased number of interneurons. Neuroscience. 2016 May 13;322:333-45

    Gkouskou KK, Ioannou M, Pavlopoulos GA, Georgila K, Siganou A, Nikolaidis G, Kanellis DC, Moore S, Papadakis KA, Kardassis D, Iliopoulos I, McDyer FA, Drakos E, Eliopoulos AG. (2016) Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis. Oncogene. 2016 May 12;35(19):2496-505.

    Vazgiouraki E, Papadakis VM, Efstathopoulos P, Lazaridis I, Charalampopoulos I, Fotakis C, Gravanis A. (2016) Application of multispectral imaging detects areas with neuronal myelin loss, without tissue labelling. Microscopy (Oxf). 2016 Apr;65(2):109-18.

    Hadjimichael C, Nikolaou C, Papamatheakis J, Kretsovali A. (2016) MicroRNAs for Fine-Tuning of Mouse Embryonic Stem Cell Fate Decision through Regulation of TGF-β Signaling. Stem Cell Reports. 8;6(3):292-301


    Bastakis GG, Savvaki M, Stamatakis A, Vidaki M, Karagogeos D. (2015) Tag1 deficiency results in olfactory dysfunction through impaired migration of mitral cells. Development. 2015 Dec 15;142(24):4318-28.

    Charlton JJ, Tsoukatou D, Mamalaki C, Chatzidakis I. (2015) Programmed death 1 regulates memory phenotype CD4 T cell accumulation, inhibits expansion of the effector memory phenotype subset and modulates production of effector cytokines. PLoS One. 10(3):e0119200

    Efstathopoulos P, Kourgiantaki A, Karali K, Sidiropoulou K, Margioris AN, Gravanis A, Charalampopoulos I. (2015) Fingolimod induces neurogenesis in adult mouse hippocampus and improves contextual fear memory. Transl Psychiatry. 2015 Nov 24;5:e685.

    Tiniakou I, Kanaki Z, Georgopoulos S, Chroni A, Van Eck M, Fotakis P, Zannis VI, Kardassis D. (2015) Natural human apoA-I mutations L141RPisa and L159RFIN alter HDL structure and functionality and promote atherosclerosis development in mice. Atherosclerosis. 2015 Nov;243(1):77-85.

    Tivodar S, Kalemaki K, Kounoupa Z, Vidaki M, Theodorakis K, Denaxa M, Kessaris N, de Curtis I, Pachnis V, Karagogeos D (2015) Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Cereb Cortex. 2015 Sep;25(9):2370-82.

    Andreadaki M, Mollenkopf HJ, Nika F, Brady D, Tewari R, Matuschewski K, Siden-Kiamos I. (2015) Global expression profiling reveals shared and distinct transcript signatures in arrested act2(-) and CDPK4(-) Plasmodium berghei gametocytes. Mol Biochem Parasitol. 201(2):100-7.

    Tiniakou I, Drakos E, Sinatkas V, Van Eck M, Zannis VI, Boumpas D, Verginis P, Kardassis D. (2015) High-Density Lipoprotein Attenuates Th1 and Th17 Autoimmune Responses by Modulating Dendritic Cell Maturation and Function. J Immunol. 194(10):4676-87

    Tampaki Z, Mwakubambanya RS, Goulielmaki E, Kaforou S, Kim K, Waters AP, Carruthers VB, Siden-Kiamos I, Loukeris TG, Koussis K. (2015) Ectopic Expression of a Neospora caninum Kazal Type Inhibitor Triggers Developmental Defects in Toxoplasma and Plasmodium. PLoS One. 2015 Mar 24;10(3):e0121379.

    Charlton JJ, Tsoukatou D, Mamalaki C, Chatzidakis I. (2015) Programmed death 1 regulates memory phenotype CD4 T cell accumulation, inhibits expansion of the effector memory phenotype subset and modulates production of effector cytokines. PLoS One. 10(3):e0119200


    Goulielmaki E, Sidén-Kiamos I, Loukeris TG (2014) Functional Characterization of Anopheles Matrix Metalloprotease 1 Reveals Its Agonistic Role during Sporogonic Development of Malaria Parasites. Infect Immun 82(11): 4865-77

    Andreadaki M, Morgan RN, Deligianni E, Kooij TW, Santos JM, Spanos L, Matuschewski K, Louis C, Mair GR, Siden-Kiamos I (2014) Genetic crosses and complementation reveal essential functions for the Plasmodium stage-specific actin2 in sporogonic development. Cell Microbiol 16(5): 751-67

    Nikoletopoulou V, Tavernarakis N (2014) Mitochondrial biogenesis and dynamics in neurodegeneration: a causative relationship. Neurochem Res 39(3): 542-5

    Gkouskou KK, Deligianni C, Tsatsanis C, Eliopoulos AG. (2014) The gut microbiota in mouse models of inflammatory bowel disease. Front Cell Infect Microbiol. 2014 Feb 28;4:28.

    Karakasilioti I, Garinis GA (2014) Tissue-specific aging: a tale of functional asymmetry. Aging (Albany NY) 6(1): 7-8


    Papadakis G, Tsortos A, Kordas A, Tiniakou I, Morou E, Vontas J, Kardassis D, Gizeli E (2013) Acoustic detection of DNA conformation in genetic assays combined with PCR. Sci Rep 3(): 2033

    Karakasilioti I, Kamileri I, Chatzinikolaou G, Kosteas T, Vergadi E, Robinson AR, Tsamardinos I, Rozgaja TA, Siakouli S, Tsatsanis C, Niedernhofer LJ, Garinis GA (2013) DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria. Cell Metab 18(3): 403-15

    Ioannou M, Alissafi T, Boon L, Boumpas D, Verginis P (2013) In vivo ablation of plasmacytoid dendritic cells inhibits autoimmunity through expansion of myeloid-derived suppressor cells. J Immunol 190(6): 2631-40

    Charlton JJ, Chatzidakis I, Tsoukatou D, Boumpas DT, Garinis GA, Mamalaki C (2013) Programmed death-1 shapes memory phenotype CD8 T cell subsets in a cell-intrinsic manner. J Immunol 190(12): 6104-14

    Kyrmizi I, Ioannou M, Hatziapostolou M, Tsichlis PN, Boumpas DT, Tassiulas I (2013) Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice. J Leukoc Biol 94(4): 751-7


    Favicchio R, Zacharakis G, Oikonomaki K, Zacharopoulos A, Mamalaki C, Ripoll J. (2012) Kinetics of T-cell receptor-dependent antigen recognition determined in vivo by multi-spectral normalized epifluorescence laser scanning. J Biomed Opt. 17:076013

    Ioannou M, Alissafi T, Lazaridis I, Deraos G, Matsoukas J, Gravanis A, Mastorodemos V, Plaitakis A, Sharpe A, Boumpas D, Verginis P. (2012) Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease. J Immunol. 188:1136-46

    Kamileri I, Karakasilioti I, Garinis G. (2012) Nucleotide Excision Repair: New Tricks with Old Bricks. Trends Genet. 28:566-73

    Kamileri I, Karakasilioti I, Sideri A, Kosteas T, Tatarakis A, Talianidis I, Garinis GA. (2012) Defective transcription initiation causes postnatal growth failure in a mouse model of NER progeria. Proceedings of the National Academy of Sciences, USA 109:2995-3000

    Tilstra J, Robinson A, Wang J, Gregg S, Clauson C, Reay D, Nasto L, Croix C, Usas A, Vo N, Huard J, Clemens P, Stolz D, Guttridge D, Watkins SC, Garinis GA, Wang Y, Niedernhoffer L, Robbins P. (2012) NF-κB inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest. 122:2601-12

    Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D. (2012) Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cereb Cortex. 22:680-92


    Clowney EJ, Magklara A, Colquitt BM, Pathak N, Lane RP, Lomvardas S. (2011) High-throughput mapping of the promoters of the mouse olfactory receptor genes reveals a new type of mammalian promoter and provides insight into olfactory receptor gene regulation. Genome Res. 21(8):1249-59

    Gregg SQ, Gutiérrez V, Robinson AR, Woodell T, Nakao A, Ross MA, Michalopoulos GK, Rigatti L, Rothermel CE, Kamileri I, Garinis G, Stolz DB, Niedernhofer LJ. (2011) A mouse model of accelerated liver aging due to a defect in DNA repair. Hepatology doi: 10.1002/hep.24713

    Lee SC, Magklara A, Smith CL. (2011) HDAC activity is required for efficient core promoter function at the mouse mammary tumor virus promoter. J Biomed Biotechnol. 2011;2011:416905

    Magklara A, Yen A, Colquitt BM, Clowney EJ, Allen W, Markenscoff-Papadimitriou E, Evans ZA, Kheradpour P, Mountoufaris G, Carey C, Barnea G, Kellis M, Lomvardas S. (2011) An epigenetic signature for monoallelic olfactory receptor expression. Cell. 13;145(4):555-70

    Ohnsorg PM, Rohrer L, Perisa D, Kateifides A, Chroni A, Kardassis D, Zannis VI, von Eckardstein A. (2011) Carboxyl Terminus of Apolipoprotein A-I (ApoA-I) Is Necessary for the Transport of Lipid-free ApoA-I but Not Prelipidated ApoA-I Particles through Aortic Endothelial Cells. J Biol Chem. 286:7744-54

    Siden-Kiamos I, Louis C, Matuschewski K. (2011) Evidence for filamentous actin in ookinetes of a malarial parasite. Mol. Biochem. Parasitol. 181:186-9

    Siden-Kiamos I, Ganter M, Kunze A, Hliscs M, Steinbüchel M, Mendoza J, Sinden RE, Louis C, Matuschewski K. (2011) Stage-specific Depletion of Myosin A Supports an Essential Role in Motility of Malarial Ookinetes. Cell Microbiol. 13:1996-2006

    Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D. (2011) Rac1-Dependent Cell Cycle Exit of MGE Precursors and GABAergic Interneuron Migration to the Cortex. Cerebral Cortex 22:680-92

    Vougioukalaki M, Kanellis DC, Gkouskou K, Eliopoulos AG. (2011) Tpl2 kinase signal transduction in inflammation and cancer. Cancer Lett. 304:80-9

    Wang W, Karagogeos D, Kilpatrick DL. (2011) The effects of Tag-1 on the maturation of mouse cerebellar granule neurons. Cell Mol Neurobiol. 31:351-6


    Martinez-Jimenez CP, Kyrmizi I, Cardot P, Gonzalez FJ, Talianidis I. (2010) Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism. Mol Cell Biol. 30:565-577.

    Chatzidakis I, Mamalaki C. (2010) T cells as sources and targets of TNF: implications for immunity and autoimmunity. Current Directions in Autoimmunity 11:105-18

    Sarasa-Renedo A, Favicchio R, Birk U, Zacharakis G, Mamalaki C, Ripoll J. (2010) Source intensity profile in noncontact optical tomography. Opt Lett. 35:34-6

    Savvaki M, Theodorakis K, Zoupi L, Stamatakis A, Tivodar S, Kyriacou K, Stylianopoulou F, Karagogeos D. (2010) The expression of TAG-1 in glial cells is sufficient for the formation of the juxtaparanodal complex and the phenotypic rescue of Tag-1 homozygous mutants. J. Neurosci 30:13943-54

    Siden-Kiamos I, Schuler H, Liakopoulos D, Louis C. (2010) An actin-related protein, in Plasmodium berghei. Mol Biochem Parasitol 173:88-96


    Garinis GA, Schumacher B. (2009) Transcription-blocking DNA damage in aging and longevity. Cell Cycle. 8:2134-5

    Garinis GA , Uittenboogaard LM , Stachelscheid H , Fousteri M , van Ijcken W , Breit TM , van Steeg H , Mullenders LH , van der Horst GT , Bruning JC , Niessen CM , Hoeijmakers JH , Schumacher B. (2009) Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nature Cell Biology 11:604-15

    Ponzi M, Sidén-Kiamos I, Bertuccini L, Currà C, Kroeze H, Camarda G, Pace T, Franke-Fayard B, Laurentino EC, Louis C, Waters AP, Janse CJ, Alano P. (2009) Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein. Cell Microbiol. 11:1272-88

    Schumacher B, Hoeijmakers JH, Garinis GA. (2009) Sealing the gap between nuclear DNA damage and longevity. Mol Cell Endocrinol. 299:112-7

    Vardouli L, Lindqvist C, Vlahou K, Loskog AS, Eliopoulos AG. (2009) Adenovirus delivery of human CD40 ligand gene confers direct therapeutic effects on carcinomas. Cancer Gene Ther. 16:848-60


    Venteclef, N., Haroniti, A., Tousaint,J-J., Talianidis, I. and Delerive, P. (2008) Regulation of Anti-atherogenic Apolipoprotein M Gene Expression by the Orphan Nuclear Receptor LRH-1. J. Biol. Chem. 283:3694 – 3701.

    Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS 2nd, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I. (2008) Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. Mol Cell. 31:531-543.

    Chatzopoulou E, Miguez A, Savvaki M, Levasseur G, Muzerelle A, Muriel MP, Goureau O, Watanabe K, Goutebroze L, Gaspar P, Zalc B, Karagogeos D, Thomas JL. (2008) Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. Journal of Neuroscience 28:7624-36

    Martin A, Aguirre J, Sarasa-Renedo A, Tsoukatou D, Garofalakis A, Meyer H, Mamalaki C, Ripoll J, Planas AM. (2008) Imaging changes in lymphoid organs in vivo after brain ischemia with three-dimensional fluorescence molecular tomography in transgenic mice expressing green fluorescent protein in T lymphocytes. Mol Imaging. 2008 Jul-Aug;7(4):157-67.

    Ma QH, Futagawa T, Yang WL, Jiang XD, Zeng L, Takeda Y, Xu RX, Bagnard D, Schachner M, Furley AJ, Karagogeos D, Watanabe K, Dawe GS, Xiao ZC. (2008) A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis. Nat Cell Biol. 10:283-94

    McLaughlin D, Vidaki M, Karagogeos D. (2008) Localization of CRMP5 mRNA by in situ hybridisation during development of the mouse forebrain. Neurosci Lett. 432:117-20

    Savvaki M, Panagiotaropoulos T, Stamatakis A, Sargiannidou I, Karatzioula P, Watanabe K, Stylianopoulou F, Karagogeos D, Kleopa KA. (2008) Impairment of learning and memory in TAG-1 deficient mice associated with shorter CNS internodes and disrupted juxtaparanodes, Mol Cell Neurosci. 39:478-90

    Sidén-Kiamos I, Louis C. (2008) Intracellular calcium levels in the Plasmodium berghei ookinete. Parasitology 135:1355-62


    Chatzidakis I, Fousteri G, Tsoukatou D, Kollias G, Mamalaki C. (2007) An essential role for TNF in modulating thresholds for survival, activation, and tolerance of CD8+ T cells. J Immunol. 178:6735-45

    Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J. (2007) Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging 6:96-107

    Meyer H, Garofalakis A, Zacharakis G, Psycharakis S, Mamalaki C, Kioussis D, Economou EN, Ntziachristos V, Ripoll J. (2007) Noncontact optical imaging in mice with full angular coverage and automatic surface extraction. Appl Opt. 46:3617-27

    Papadaki C, Alexiou M, Cecena G, Verykokakis M, Bilitou A, Cross JC, Oshima RG, Mavrothalassitis G. (2007) Transcriptional repressor erf determines extraembryonic ectoderm differentiation. Mol Cell Biol. 27:5201-13

    Stanulovic VS, Kyrmizi I, Kruithof-de Julio M, Hoogenkamp M, Vermeulen JL, Ruijter JM, Talianidis I, Hakvoort TB, Lamers WH. (2007) Hepatic HNF4 alpha deficiency induces periportal expression of glutamine synthetase and other pericentral enzymes. Hepatology 45:433-44


    Hatzis P, Kyrmizi I, Talianidis I. (2006) Mitogen-activated protein kinase-mediated disruption of enhancer-promoter communication inhibits hepatocyte nuclear factor 4alpha expression. Mol Cell Biol. 26:7017-29

    Katidou M, Theodorakis K, Renieri E, …, Karagogeos D. (2006) The bHLH gene NSCL1 in the vertebrate nervous system: expression and functional studies. International Journal Of Developmental Neuroscience 24:563

    Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I. (2006) Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes and Development 20:2293-305


    Boulias K, Katrakili N, Bamberg K, Underhill P, Greenfield A, Talianidis I. (2005) Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP. EMBO J. 24:2624-33

    Chalkiadaki A, Talianidis I. (2005) SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin. Mol Cell Biol. 25:5095-105

    Denaxa M, Kyriakopoulou K, Theodorakis K, Trichas G, Vidaki M, Takeda Y, Watanabe K, Karagogeos D. (2005) The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons. Dev Biol. 288:87-99

    Ekonomou A, Kazanis I, Malas S, Wood H, Alifragis P, Denaxa M, Karagogeos D, Constanti A, Lovell-Badge R, Episkopou V. (2005) Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1. PLoS Biology 3:e186

    Fragkos M, Anagnou NP, Tubb J, et al. (2005) Use of the hereditary persistence of fetal hemoglobin 2 enhancer to increase the expression of oncoretrovirus vectors for human gamma-globin. Gene Therapy 12:1591-600

    Kouskouti A, Talianidis I. (2005) Histone Modifications Defining Active Genes Persist After Transcriptional And Mitotic Inactivation. Embo J. 24:347-57

    Soares, S., Traka, M., vonBoxberg, Y., Karagogeos, D. and Nothias, F. (2005) Neuronal and glial expression of the adhesion molecule TAG-1 is regulated after peripheral nerve lesion or central neurodegeneration of adult nervous system. European Journal of Neuroscience 21:1169-80


    Anagnou NP. (2003) Molecular mechanisms of fetal globin gene activation and silencing. Blood Cells Molecules And Diseases 31:127-127

    Mamalaki A, Gritzapis AD, Kretsovali A, Belimezi M, Papamatheakis J, Perez SA, Papamichail M, Baxevanis CN. (2003) In vitro and in vivo antitumor activity of a mouse CTL hybridoma expressing chimeric receptors bearing the single chain Fv from HER-2/neu-specific antibody and the gamma-chain from Fc(epsilon)RI. Cancer Immunology Immunotherapy 52:513-22

    Traka M, Goutebroze L, Denisenko N, Bessa M, Nifli A, Havaki S, Iwakura Y, Fukamauchi F, Watanabe K, Soliven B, Girault JA, Karagogeos D. (2003) Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers. Journal Of Cell Biology 162:1161-72


    De Diego I, Kyriakopoulou K, Karagogeos D, Wassef M. (2002) Multiple influences on the migration of precerebellar neurons in the caudal medulla. Development 129:297-306


    Denaxa M, Chan Ch, Schachner M, Parnavelas Jg, Karagogeos D. (2001) The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system. Development 128:4635-44

    Pavlou O, Theodorakis K, Falk J, Kutsche M, Schachner M, Faivre-Sarrailh C, Karagogeos D. (2002) Analysis of interactions of the adhesion molecule TAG-1 and its domains with other immunoglobulin superfamily members. Molecular And Cellular Neuroscience 20:367-81

    Traka M, Dupree Jl, Popko B, Karagogeos D. (2002) The neuronal adhesion protein TAG-1 is expressed by Schwann cells and oligodendrocytes and is localized to the juxtaparanodal region of myelinated fibers. Journal Of Neuroscience 22:3016-24


    Pascolo S, Tsoukatou D, Mamalaki C. (1999) Identification of thymus specific and developentally regulated genes, by an improved version of the mRNA differential display technique. Devel Immun 7:1-7

    Virgintino D, Ambrosini M, D'Errico P, Bertossi M, Papadaki C, Karagogeos D, Gennarini G. (1999) Regional distribution and cell-type specific expression of the mouse F3 axonal glycoprotein: a developmental study. J Comp Neurol 413:357-72


    Buttiglione M, Revest JM, Pavlou O, Karagogeos D, Furley A, Rougon G, Faivre-Sarrailh C. (1998) A functional interaction between the neuronal adhesion molecules TAG-1 and F3 modulates neurite outgrowth and fasciculation of cerebellar granule cells. J Neurosci. 18:6853-70


    Bailly Y, Kyriakopoulou K, Delhaye-Bouchaud N, Mariani J, Karagogeos D. (1996) Cerebellar granule cell differentiation in mutant and X-irradiated rodents revealed by the expression of the neural adhesion molecular TAG-1. J Com Neurol. 369:150-61

    Mamalaki C., Murdjeva M., Tolaini M., Norton T., Chandler P., Townsend A., Simpson E. Kioussis D. (1996) Tolerance in TcR/cognate antigen double transgenic mice by incomplete thymic and peripheral receptor down regulation. Dev. Immunol. 4:299-315

    Mice generated

    Evi Goulielmaki, Maria Tsekrekou, Nikos Batsiotos, Mariana Ascensão-Ferreira, Eleftheria Ledaki, Kalliopi Stratigi, Georgia Chatzinikolaou, Pantelis Topalis, Theodore Kosteas, Janine Altmüller, Jeroen A. Demmers, Nuno L. Barbosa-Morais, George A. Garinis (2020) The Splicing Factor XAB2 interacts with ERCC1-XPF and XPG for RNA-loop processing during mammalian development bioRxiv 2020.07.20.211441; doi:

    Chatzinikolaou G, Apostolou Z, Aid-Pavlidis T, Ioannidou A, Karakasilioti I, Papadopoulos GL, Aivaliotis M, Tsekrekou M, Strouboulis J, Kosteas T, Garinis GA. (2017) ERCC1-XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes. Nat Cell Biol. 19(5):421-432.

    Twigg SR, Vorgia E, McGowan SJ, Peraki I, Fenwick AL, Sharma VP, Allegra M, Zaragkoulias A, Sadighi Akha E, Knight SJ, Lord H, Lester T, Izatt L, Lampe AK, Mohammed SN, Stewart FJ, Verloes A, Wilson LC, Healy C, Sharpe PT, Hammond P, Hughes J, Taylor S, Johnson D, Wall SA, Mavrothalassitis G, Wilkie AO (2013) Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis. Nat Genet 45(3): 308-13

    Gazouli M, Katsantoni E, Kosteas T, Anagnou NP. (2009) Persistent fetal gamma-globin expression in adult transgenic mice following deletion of two silencer elements located 3' to the human Agamma-globin gene. Mol Med. 15:415-24

    Denaxa M, Pavlou O, Tsiotra P, Papadopoulos GC, Liapaki K, Theodorakis K, Papadaki C, Karagogeos D, Papamatheakis J. (2003) The upstream regulatory region of the gene for the human homologue of the adhesion molecule TAG-1 contains elements driving neural specific expression in vivo. Molecular Brain Research 118:91-101

    Drabek D, Zagoraiou L, Dewit T, Langeveld A, Roumpaki C, Mamalaki C, Savakis C, Grosveld F. (2003) Transposition Of The Drosophila Hydei Minos Transposon In The Mouse Germ Line. Genomics 81:108-11

    Kosteas T, Katsantoni E, Strouboulis J, Grosveld F, Kourouniotis K, Mamalaki K, Anagnou NP. (2003) High levels of A gamma-globin gene expression at the adult stage of transgenic mice in the absence of silencers located 3 ' to the A gamma-globin gene. Blood Cells Molecules And Diseases 31:149-150

    Zagoraiou L, Drabek D, Alexaki S, Guy Ja, Klinakis Ag, Langeveld A, Skavdis G, Mamalaki C, Grosveld F, Savakis C. (2001) In Vivo Transposition Of Minos, A Drosophila Mobile Element, In Mammalian Tissues. Proceedings Of The National Academy Of Sciences Of The United States Of America 98:11474-78