Gene Regulation & Epigenetics

Despina Alexandraki

We are interested on the mechanisms governing gene expression regulated by DNA-binding transcription factors and chromatin regulators in response to environmental changes. Our reference system is metalloregulated...

Gene Regulation

Dimitris Kardassis

Cardiovascular disease (CVD) is the leading cause of death in Western societies. Genetic defects in key genes of lipoprotein metabolism and pathological conditions such as chronic inflammation, diabetes, obesity and the metabolic...

Gene Regulation

Androniki Kretsovali

Embryonic stem (ES) cells offer great promise for cell replacement therapies since they are highly proliferating cells that are able to self-renew and retain the capacity to differentiate along almost all possible differentiation...

Chromatin & Gene Expression

George Mavrothalassitis

Our long standing interest is the signal regulated transcriptional control in development and disease. Specifically the ETS genes within the RTK/ras/erk pathway in normal and tumor development...

Gene Regulation

Joseph Papamatheakis

Since 2014, the group has shifted research activities to focus on cancer biology. Recent advances in Molecular Biology had a dramatic impact in understanding the mechanisms that drive oncogenic pathways...

Chromatin & Gene Expression

Charalampos G. Spilianakis

Regulation of gene expression can be accomplished "in cis" by several regulatory elements exerting their action on physically linked genes on the same chromosome. A "trans" regulation aspect of gene expression...

Chromatin & Gene Expression

John Strouboulis

Our research addresses the transcriptional and epigenetic regulation of hematopoiesis by focusing on the characterization of transcription factor and associated co-factor functions in red blood cell differentiation...

Molecular Hematopoiesis

Iannis Talianidis

We study epigenetic mechanisms regulating liver development, hepatocarcinogenesis and metabolism. Our research aims at understanding the interplay between chromatin modifying enzymes...

Epigenetics