Despina Alexandraki
We are interested on the mechanisms governing gene expression regulated by DNA-binding transcription factors and chromatin regulators in response to environmental changes. Our reference system is metalloregulated...
We are interested on the mechanisms governing gene expression regulated by DNA-binding transcription factors and chromatin regulators in response to environmental changes. Our reference system is metalloregulated...
Cardiovascular disease (CVD) is the leading cause of death in Western societies. Genetic defects in key genes of lipoprotein metabolism and pathological conditions such as chronic inflammation, diabetes, obesity and the metabolic...
Our main research interests are the investigation of molecular processes that regulate embryonic stem cell pluripotency and neuronal regeneration...
Our long standing interest is the signal regulated transcriptional control in development and disease. Specifically the ETS genes within the RTK/ras/erk pathway in normal and tumor development...
Since 2014, the group has shifted research activities to focus on cancer biology. Recent advances in Molecular Biology had a dramatic impact in understanding the mechanisms that drive oncogenic pathways...
Regulation of gene expression can be accomplished "in cis" by several regulatory elements exerting their action on physically linked genes on the same chromosome. A "trans" regulation aspect of gene expression...
We study epigenetic mechanisms regulating liver development, hepatocarcinogenesis and metabolism. Our research aims at understanding the interplay between chromatin modifying enzymes...